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Microsatellite

microsatellite

(Science: molecular biology) short sequences of di- or trinucleotide repeats of very variable length distributed widely throughout the genome. Using pCR primers to the unique sequences upstream and downstream of a microsatellite their location and polymorphism can be determined and the technique is extensively used in investigating genetic associations with disease.


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Need help identifying these bones

I'm afraid that even if police considered it as human bones, they would perform only microsatellite test, not whole genome sequencing, which would you need to identify the species (or at least partial sequencing).

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by JackBean
Tue Dec 18, 2012 8:40 pm
 
Forum: Human Biology
Topic: Need help identifying these bones
Replies: 8
Views: 873

microsatellite instability

Actually I just came across one answer: "factors such as increased microsatellite instability have been associated with improved survival in patients with right-sided lesions."

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by kk
Mon Aug 13, 2012 1:32 pm
 
Forum: Molecular Biology
Topic: microsatellite instability
Replies: 1
Views: 806

microsatellite instability

My question is what is the therapeutic advantage if someone with a colorectal tumor is diagnosed being microsatellite instable. Tx.

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by kk
Wed Aug 08, 2012 11:21 am
 
Forum: Molecular Biology
Topic: microsatellite instability
Replies: 1
Views: 806

finding out if resistance is from mutation or hybridization?

microsatellite by itself gives resistance?

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by JackBean
Sun Nov 13, 2011 12:10 pm
 
Forum: Genetics
Topic: finding out if resistance is from mutation or hybridization?
Replies: 4
Views: 1626

PCR trouble

Hello, I have a rather odd problem with my PCR... I'm performing microsatellite analysis of molted feathers. The DNA isolation is done with a standard tissue kit and after that the PCR. For the past six months everything was fine and then suddenly after ...

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by Harmakhis
Wed Jul 06, 2011 11:20 am
 
Forum: Molecular Biology
Topic: PCR trouble
Replies: 3
Views: 1886
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