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Dictionary » M » Mice Micemice The common name for the species mus musculus. ![]()
Please contribute to this project, if you have more information about this term feel free to edit this page ![]()
Results from our forumConditional knockout mouse... am using transgenic mouse where my gene of interest is floxed. When I cross this mouse line with Tamoxifen inducible Cre line, CAGGCre-ERTM, I get mice with with heterozygous Cre and floxed gene of interest. The experimental plan was to isolate myoblasts from these mice and induce Cre in cell culture ...
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Knockout miceI ran across a paper with the genetic version of knockdown mice this morning. "Knockdown of Cdc42 in the developing retina was achieved by crossing Cdc42 floxed mice [29] with mice expressing cre recombinase under the control of the α element of ...
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Re: Knockout mice"Does this imply that all the somatic cells in the mice contain 1 copy of the functional gene and 1 copy of the non-functional gene? " Yes. "Would this then mean that each cell is expressing the protein to some extent?" Likely yes, ...
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Knockout miceThanks for your response! Does this imply that all the somatic cells in the mice contain 1 copy of the functional gene and 1 copy of the non-functional gene? Would this then mean that each cell is expressing the protein to some extent? What confuses me is that ...
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Knockout miceCan someone please explain how it is possible to have a heterozygous knock out mouse? If a gene is "knocked-out," how can the mouse be heterozygous for the gene? Will the mouse still produce express this "knocked-out" gene? Thanks very much!
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