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Mediators

mediator

An object or substance by which something is mediated, such as

1. (Science: anatomy) A structure of the nervous system that transmits impulses eliciting a specific response.

2. (Science: chemistry) A chemical substance (transmitter substance) that induces activity in an excitable tissue, such as nerve or muscle, or

3. (Science: cell biology) A substance released from cells as the result of the interaction of antigen with antibody or by the action of antigen with a sensitised lymphocyte.


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Evolution of itch

... etc. etc.) are not relevant, because the reason for those is quite likely just a side effect of the release of histamine and other such cellular mediators - and in any case the etiology of the problem is entirely different. But back to the original problem. Quite obviously itching, unlike pain, ...

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by biohazard
Wed Mar 07, 2012 10:10 am
 
Forum: Evolution
Topic: Evolution of itch
Replies: 3
Views: 2167

Immunology

... as well. Also, many cytokine reactions function in a similar manner: cells of the innate or adaptive immune system may secrete cytokines and other mediators that also affect the cells of the "opposite" system.

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by biohazard
Tue May 24, 2011 11:02 am
 
Forum: Human Biology
Topic: Immunology
Replies: 2
Views: 2110

Stomach bloating and weight gain

... nervous system, thereby causing irritable bowel syndrome. Using ultrafast optical measuring methods, the researchers were able to demonstrate that mediators from mast cells and enterochromaffin cells directly activate the nerve cells in the bowel. This hypersensitivity of the enteric nervous system ...

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by CheeMiss
Sat Sep 04, 2010 9:05 pm
 
Forum: Physiology
Topic: Stomach bloating and weight gain
Replies: 451
Views: 2542176

Re: Stomach bloating and weight gain

... and betamethasone are commonly used and prescribed corticosteroid medications that function in blocking the pro-inflammatory chemical mediators in the body including the compounds such as histamine, some of the prostaglandins and the compounds called leukotrienes. Scientists believe ...

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by Jennuan
Wed Oct 29, 2008 4:21 am
 
Forum: Physiology
Topic: Stomach bloating and weight gain
Replies: 451
Views: 2542176

What is cancer?(in genral)

yes, cancer can be very painful... multiple mechanisms: 1) tumours have ways of inducing inflammation via release of many inflammatory mediators (cytokines, prostaglandins, leukotrienes) -> thus inflammatory pain 2) the tumours can damage activate and damage sensory nerves -> neuropathic ...

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by Revenged
Mon Feb 25, 2008 4:34 pm
 
Forum: General Discussion
Topic: What is cancer?(in genral)
Replies: 8
Views: 6409
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