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Maturation

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1. Achievement of full development or growth.

2. Developmental changes that lead to maturity.

3. Processing of a macromolecule; e.g., posttranscriptional modification of rna or posttranslational modification of proteins.

Origin: L. Maturatio, a ripening, fr. Maturus, ripe (biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; he proposed an indicator of osseous development in children.


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Animal cell nucleus shape changes

... cell matures. This is well evident in, for example, neutrophilic leukocytes whose nuclei become lobular and very irregular-shaped during the cell maturation (but still follows a defined and controlled pathway). Another good example is the red blood cell, who has a nucleus in immature stages (erythroblast) ...

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by biohazard
Mon Nov 12, 2012 2:04 pm
 
Forum: Cell Biology
Topic: Animal cell nucleus shape changes
Replies: 7
Views: 9768

Idea to determine order of assembly of spliceosome

... is unknown to us prior to the appearance of incremental increase of mass). The mass should continue to increase with specific amounts during the maturation. Re-running this test should show a similar pattern of mass increase at specific points in time if it is the snRNP:s mass increase we are ...

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by nukeman
Mon May 28, 2012 7:48 pm
 
Forum: Molecular Biology
Topic: Idea to determine order of assembly of spliceosome
Replies: 15
Views: 7817

Re:

... they replicate? Or do white blood cells turn to red when they age? Immature red blood cells each contain a nucleus, containing DNA. However, upon maturation they then lose their nuclei (due to certain proteins disposing of it), with this they lose their DNA. They do this to make more room for ...

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by IceIcebaby
Thu May 17, 2012 1:05 pm
 
Forum: Genetics
Topic: DNA analysis
Replies: 21
Views: 16642

Evolution and hatchery populations

... thinks they are dealing with here. How do they differentiate the groups in a wild-caught population? Is it collection times, size (quicker maturation doesn't necessarily mean smaller breeders), or some other attribute? There's so much here that's unclear. If it's collection times, they ...

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by Darby
Thu Apr 05, 2012 4:36 pm
 
Forum: Evolution
Topic: Evolution and hatchery populations
Replies: 5
Views: 2817

Learning tissue culture, specifically moDC generation

... have an access to a cytometer, use of antibodies for something like CD14, CD83 and CD86 (if I recall correctly) helps to evaluate the degree of maturation of your cells. Disclaimer: the above is written based on what I remember of my past protocols, so some errors may exist. Check the study ...

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by biohazard
Fri Feb 03, 2012 2:09 pm
 
Forum: Cell Biology
Topic: Learning tissue culture, specifically moDC generation
Replies: 2
Views: 2275
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