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Maternal inheritance



A form of inheritance wherein the traits of the offspring are maternal in origin due to the expression of extranuclear DNA present in the ovum during fertilization.


Some of the traits inherited by the offspring can be solely attributed to the genetic material transmitted by the mother to her offspring. It is because during the union of gametes the ovum retains its mitochondria. Mitochondria are organelles that contain their own set of genes. It is a popular notion that most of the mitochondria acquired by the offspring are of maternal origin. When a sperm fertilizes an ovum, only its nuclear genetic material contained within the head is allowed to combine with that of the ovum while its midpiece and tail (with comparatively fewer mitochondria) are lost or disintegrated. Hence, hereditary diseases associated with faulty mitochondrial DNA are said to be inherited solely from the mother. These traits are also described as maternal effect. However, recent studies indicate that paternal mitochondrial DNA somehow gets into the ovum and thus a faulty paternal mitochondrial DNA can also be passed on to the offspring, debunking the precept that mitochondrial DNA (and therefore mitochondrial diseases) are solely maternal in origin.



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Do you mean genetically, where it is used to determine maternal inheritance? I'm not sure really, but I think this will be the case, since at the end the results ...

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by SWEngineer
Thu Nov 17, 2011 8:38 am
Forum: Cell Biology
Topic: Methods of analysis of mtDNA
Replies: 2
Views: 1336

Methods of analysis of mtDNA

Do you mean genetically, where it is used to determine maternal inheritance?

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by aptitude
Thu Nov 17, 2011 1:08 am
Forum: Cell Biology
Topic: Methods of analysis of mtDNA
Replies: 2
Views: 1336

Mitochondrial inheritance

I have read that the mitochondria of a zygote are all of maternal origin. Therefore, mitochondrial genes come from the mother. But, during fertilization the sperm has, in the middle piece, some mitochondria. Don't they get into the ovum and hence in ...

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by Adz795
Fri Aug 26, 2011 5:35 am
Forum: Human Biology
Topic: Mitochondrial inheritance
Replies: 3
Views: 4058

assignment help: genetic cross

Ok for this question you need to do a dihybrid cross to show inheritance of two traits, you are only told that each person is heterozygous for both gametes so you need to show all possibilities, for maternal (female) gametes across the top the four possibilities would be: TH, Th, ...

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by Kezzer
Sun Jan 02, 2011 4:42 pm
Forum: Genetics
Topic: assignment help: genetic cross
Replies: 6
Views: 3870

mitochondrial inheritance questions

... in mitochondrial DNA are usually transmitted in a uniparental-maternal fashion in mammals) a: the females who had offspring without hearing ... for the loss of function in the mutant tRNA gene. c: Biparental inheritance of mitochondrial DNA caused some of the offspring to escape hearing ...

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by geneticsquest
Mon Jul 12, 2010 7:24 pm
Forum: Genetics
Topic: mitochondrial inheritance questions
Replies: 1
Views: 2723

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