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Mast cell

Mast cell

(Science: cell biology, immunology) resident cell of connective tissue that contains many granules rich in histamine and heparan sulphate.

release of histamine from mast cells is responsible for the immediate reddening of the skin in a weal and flare response. Very similar to basophils and possibly derived from the same stem cells.

two types of mast cells are now recognised, those from connective tissue and a distinct set of mucosal mast cells, the activities of the latter are T-cell dependent.


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The Immune System - Recognition in innate immunity. How?

The innate immune system has many components (located on the cell surface or secreted into plasma, for example), but in general they target ... is capable of binding with high affinity to the surface of basophils and mast cells (Fce receptors). They also have different kind of disulphide bonding ...

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by biohazard
Tue May 12, 2009 7:43 am
 
Forum: Cell Biology
Topic: The Immune System - Recognition in innate immunity. How?
Replies: 1
Views: 1273

Gene activation?

Wheel, An "oncogene" is a gene that causes a cell to become cancerous when it is active/inactive. These genes usually have ... turn cancerous. (An example of this is the c-kit transmembrane protein in mast cells causing mastocytosis). Scenario 2: Gene Y inhibits cell division when ...

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by BioLad
Thu Feb 14, 2008 5:30 pm
 
Forum: Genetics
Topic: Gene activation?
Replies: 2
Views: 686

Re: An allergy response...

... immediate immmune response that produces IgE antibodies and a delayed T-cell response. allergic reactions only refers to type I hypersensitivity i.e. immediate IgE release from mast cells and basophils... e.g. hayfever, peanut allergy... coeliac disease is a cell ...

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by Revenged
Thu Nov 15, 2007 2:38 pm
 
Forum: Human Biology
Topic: Allergy questions
Replies: 18
Views: 2365

regarding T helper 2!

... Why do we treat it after the chemical mediators are released from the mast cell? in other words, can we prevent the allergic reaction caused by a reexposure to a specific ...

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by Yazeed
Sat Jun 02, 2007 6:54 pm
 
Forum: Cell Biology
Topic: regarding T helper 2!
Replies: 1
Views: 366

Electron Micrograph of vesicles...

Thank you so much for all your replies! It is indeed a mast cell, I forgot to meantion that! Sorry! That fact meant nothing to me, so I guess that's why I forgot ...

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by IbelieveIAm
Mon May 28, 2007 10:24 pm
 
Forum: Cell Biology
Topic: Electron Micrograph of vesicles...
Replies: 5
Views: 835
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