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Mast cell

Mast cell

(Science: cell biology, immunology) resident cell of connective tissue that contains many granules rich in histamine and heparan sulphate.

release of histamine from mast cells is responsible for the immediate reddening of the skin in a weal and flare response. Very similar to basophils and possibly derived from the same stem cells.

two types of mast cells are now recognised, those from connective tissue and a distinct set of mucosal mast cells, the activities of the latter are T-cell dependent.


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Immunology: Th1/Th2 vs cellular/humoral responses

... effect: There is no such direct CD4+ response as there is with CD8+ T cells, B cells, or cells of the innate immune system. CD4+ cells function ... that promote IgE formation. IgE, in turn, binds to basophils and mast cells and when an allergen is bound by its specific IgE, it cross-links ...

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by biohazard
Tue Nov 02, 2010 9:35 am
 
Forum: Cell Biology
Topic: Immunology: Th1/Th2 vs cellular/humoral responses
Replies: 10
Views: 42796

Re:

... in overdrive mode, does create a lot of problems. pls. google search: mast cells, ketotifen and search around the links for something that matches your description. Again, ...

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by CheeMiss
Wed Sep 15, 2010 10:40 pm
 
Forum: Physiology
Topic: Stomach bloating and weight gain
Replies: 452
Views: 2679385

Re: Stomach bloating and weight gain

... my GP to prescribe it) and we are finding it to be helpful. It is a Mast Cell stabiliser. That is what the German Researchers used! I found that quote on this page, ...

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by CheeMiss
Sun Sep 05, 2010 2:54 am
 
Forum: Physiology
Topic: Stomach bloating and weight gain
Replies: 452
Views: 2679385

Re: Stomach bloating and weight gain

... excited. Quote from below link, found at very bottom of page: "The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms ...

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by CheeMiss
Sun Sep 05, 2010 2:04 am
 
Forum: Physiology
Topic: Stomach bloating and weight gain
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Re: Cytokine - Receptor concepts

... by T lymphocites. Otherwise, T lymphocites can be usefull in B cell activation and antibody production, here it’s named T helper cell, and ... placental transfer), IgE (acts in immunity against helminthes (worms), mast cell degranulation or immediate hypersensitivity) and IgA (acts in mucosal ...

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by marla
Tue Jun 01, 2010 9:08 pm
 
Forum: Cell Biology
Topic: Cytokine - Receptor concepts
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