Dictionary » M » Marker gene

Marker gene

Definition

noun, plural: marker genes

(genetics) A gene with known physical location, easily detectable phenotype, and whose pattern of inheritance can be followed.


Supplement

These markers are used to trace or identify specific region of a gene (especially one that is associated with an inherited disease) on a particular chromosome. These markers can be an enzymatic reporter gene, a selectable marker conferring antibiotic resistance or a cell membrane protein with a characteristic epitope.


Also called: genetic marker, DNA marker.
See also: genetic map.


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gene knockout mice

... different in the different areas of the brain, so an inactivation of a gene only in striatal astrocytes with a pure genetic approach is not possible. ... AAV containing the Cre under an astrocytic promoter and a fluorescent marker and inject stereotactically in the striatum. This will not be 100% ...

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by animodel123
Wed Mar 18, 2015 6:46 am
 
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Topic: gene knockout mice
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Re: How

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by Helics
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cell specific markers

Do such genetic markers exist? Markers that are present in one population (at least to a certain percentage) but not in another? ...

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by MarkHolland
Sat Mar 30, 2013 3:16 pm
 
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Topic: cell specific markers
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Orientation of genes

"to be cloned" part is not needed. Sorry When making a gene construct (before inserting into an expression vector), do we have to place the desired gene, the reporter gene and the marker gene in any specific direction or orientation? I have seen in most cases the ...

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by Sue4
Mon Jan 28, 2013 9:03 pm
 
Forum: Molecular Biology
Topic: Orientation of genes
Replies: 2
Views: 1473

Orientation of genes

When making a gene construct to be cloned, do we have to place the desired gene, the reporter gene and the marker gene in any specific direction or orientation? I have seen in most cases the desired gene and the reporter ...

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by Sue4
Mon Jan 28, 2013 8:23 pm
 
Forum: Molecular Biology
Topic: Orientation of genes
Replies: 2
Views: 1473
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