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Dictionary » M » Marker

Marker

Definition

noun, plural: markers

(general) Anything that marks or is used to mark, e.g. a location.

(genetics) A gene or DNA sequence with known physical location, and whose pattern of inheritance can be followed.


Supplement

In genetics, markers act as chromosomal landmarks. They are used to trace or identify specific region of a gene (especially one that is associated with an inherited disease) on a chromosome. They are also used to determine a linkage group or a recombination event.


Also called: (genetics) genetic marker, marker gene, DNA marker.
See also: genetic map.


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... Sorry When making a gene construct (before inserting into an expression vector), do we have to place the desired gene, the reporter gene and the marker gene in any specific direction or orientation? I have seen in most cases the desired gene and the reporter gene have placed in one direction ...

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Orientation of genes

When making a gene construct to be cloned, do we have to place the desired gene, the reporter gene and the marker gene in any specific direction or orientation? I have seen in most cases the desired gene and the reporter gene have placed in one direction and the marker gene ...

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Reporter gene without fusion

... we monitor the foreign gene expression if we place the reporter gene under a different promoter? If not, what is the use of placing a selectable marker and a reporter gene under the same construct (without a fusion) ? Thank you Regards :)

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