Dictionary » M » Marker



noun, plural: markers

(general) Anything that marks or is used to mark, e.g. a location.

(genetics) A gene or DNA sequence with known physical location, and whose pattern of inheritance can be followed.


In genetics, markers act as chromosomal landmarks. They are used to trace or identify specific region of a gene (especially one that is associated with an inherited disease) on a chromosome. They are also used to determine a linkage group or a recombination event.

Also called: (genetics) genetic marker, marker gene, DNA marker.
See also: genetic map.

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gene knockout mice

... You might combine genetics with viral infection. You might produce an AAV containing the Cre under an astrocytic promoter and a fluorescent marker and inject stereotactically in the striatum. This will not be 100% efficient, but might be sufficient for certain experiments. With neurons it ...

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by animodel123
Wed Mar 18, 2015 6:46 am
Forum: Genetics
Topic: gene knockout mice
Replies: 1
Views: 218

looking for ciz1 specifically affects sensitivity?

if the alternative form is marker, than probably the normal form is not affected by cancer, is it?

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by JackBean
Thu May 15, 2014 8:03 pm
Forum: Molecular Biology
Topic: looking for ciz1 specifically affects sensitivity?
Replies: 1
Views: 1471


http://www.ncbi.nlm.nih.gov/pubmed/20677001 First you use a sequence with the selection marker (as usually), but that is later excised by I-SceI cleavage and the second Red recombination.

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by JackBean
Sun May 11, 2014 6:35 pm
Forum: Genetics
Topic: Mutagenesis
Replies: 2
Views: 1563

plasmid extraction on 1.5% agarose gel

So I have two bands, the smaller that is around 8-9kb based on the marker ( my plasmids should be 8-9 kb), what is the upper band? Also I have three plasmids and I did this in a set of four replicates

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by cah2010
Wed Dec 18, 2013 2:23 am
Forum: Molecular Biology
Topic: plasmid extraction on 1.5% agarose gel
Replies: 5
Views: 2726

Need an help about Drosophila genetics

... there are two copies just like in humans: 2nd chromosome: UAS-UPRT is homozygous 3rd Chromosome: One chromosomes carries Repo. The other carries a marker TM6 which gives flies short bristles. You are starting from: 2nd chromosomes UAS-UPRT homozygous ; 3rd chromosomes wild-type homozygous crossed ...

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by golgicik
Wed Oct 30, 2013 8:46 pm
Forum: Genetics
Topic: Need an help about Drosophila genetics
Replies: 5
Views: 3785
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