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Mariner

Mariner

group of transposons with broad phylogenetic distribution (arthropods, nematodes, planaria, humans). Mariner elements consist of a transposase gene flanked by short inverted repeats. Nature 378:672


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The Fiber Disease

... genetic transformation, and insertional mutagenesis in somatic cells and viral vectors for use as therapeutics. The Himar1 transposon (part of the mariner family of transposons) functions in any organism, making it a general-purpose transposon system that will eliminate the need for researchers ...

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by Nadas Moksha
Sat Dec 09, 2006 7:58 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5414759

The Fiber Disease

... synthesis in fish. Demonstration of germline transmission using transposons such as Tol2 (45) and Sleeping Beauty (SB) (90), a member of the Tc1/mariner family, highlights the potential of transposons for zebrafish transgenesis, mutagenesis, and application to functional genomics. Tc1/mariner ...

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by codon blue
Tue Nov 14, 2006 9:12 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5414759


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