Mariner

... genetic transformation, and insertional mutagenesis in somatic cells and viral vectors for use as therapeutics. The Himar1 transposon (part of the mariner family of transposons) functions in any organism, making it a general-purpose transposon system that will eliminate the need for researchers ...

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... synthesis in fish. Demonstration of germline transmission using transposons such as Tol2 (45) and Sleeping Beauty (SB) (90), a member of the Tc1/mariner family, highlights the potential of transposons for zebrafish transgenesis, mutagenesis, and application to functional genomics. Tc1/mariner ...

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