The enzyme that catalyzes the oxidative decarboxylation of (S)-malate to pyruvate, with the concomitant release of carbon dioxide and conversion of NADP+ to NADPH.
This enzyme catalyzes the chemical reaction as follows:
(S)-malate + NADP+ → pyruvate + CO2 + NADPH
- (S)-malate:NAD+ oxidoreductase (decarboxylating) (chemical name)
- pyruvic-malic carboxylase
- NAD+-specific malic enzyme
- NAD+-malic enzyme
User Contributions / Comments:
- An enzyme which catalyzes the oxidative decarboxylation of malate to pyruvate and carbon dioxide concomitantly reducing NADP+ to NADPH. The NADPH generated by malic enzyme is used for the reductive biosynthesis of molecules such as fatty acids.