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Major histocompatibility antigens

Major histocompatibility antigen

(Science: immunology) a set of plasmalemmal glycoprotein antigens involved in rapid (e.g. 7 days in the mouse) graft rejection and other immune phenomena. The minor histocompatibility antigens are involved in much slower rejection phenomena. The major antigens show remarkable polymorphism and occur as class i and class ii types in mammals, birds may have a class iii molecule as well.

See: histocompatibility antigens, mhc restriction.

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I have got some BIG issues! forgive the long post

... of seemingly no clinical importance. The ABH antigens are not primary gene products but instead ... The human HLA system referred to as MHC (major histocompatibility complex) is located on the chromosome ...

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by saddy51
Sun Jan 04, 2015 10:39 am
Forum: Genetics
Topic: I have got some BIG issues! forgive the long post
Replies: 1
Views: 1933

Cancer Vaccines: Unanswered Questions

... • Is there a ‘best platform’ to deliver antigens to the immune system for a therapeutic ... peptides but not to the HSPs themselves. The major mechanism of action is thought to be the ability of HSPs to prime peptide-specific major histocompatibility complex (MHC) class I-restricted ...

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by conecticut
Mon Aug 01, 2005 1:45 pm
Forum: Genetics
Topic: Cancer Vaccines: Unanswered Questions
Replies: 3
Views: 8695

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