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Macrophage

Macrophage

Relatively long lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), kupffer cells of the liver and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa and tumour cells, release substances that stimulate other cells of the immune system and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or langhans giant cells. A large phagocyte; some are fixed and other circulate in the blood stream.A type of white blood cell deriving from monocytes whose primary jobs are to remove wasteful material in the body and to break down red blood cells which are at the end of their life cycle.


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Nuclei fills the whole cell

... They can uptake GFP proteins from other tissue. People think they might be drosophila kidney, but I dont believe. I think they might be similar to macrophage. Most interestingly, lately I found that, in those cells from the aged adult flies (only from aged fly, but not from young fly), the whole ...

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by genomy
Mon Mar 05, 2012 7:36 pm
 
Forum: Cell Biology
Topic: Nuclei fills the whole cell
Replies: 0
Views: 507

Does Langerhan cell in epidermis change to macrophage?

Langerhans cells are antigen presenting cells and macrophages are phagocytes. They both act in the immune responds. Macrophages are found in the tissue where monocytes(lymphocytes) in the blood, slips it way through into the tissue and differentiate into macrophages. Langerhans cells are found in th...

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by AUY11345303
Tue Dec 20, 2011 3:58 pm
 
Forum: Human Biology
Topic: Does Langerhan cell in epidermis change to macrophage?
Replies: 0
Views: 687

Can you recommend a vector?

... (as detected by western and qPCR) of the transgene for 8-12 cell passages, but then the CMV becomes silenced. We are working in Raw 267.4 cells, a macrophage line which are apparently notorious for this. So far i am looking for a human promoter within the plasmid which is inducible by the addition ...

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by JimmyTee
Wed Jun 15, 2011 3:17 pm
 
Forum: Molecular Biology
Topic: Can you recommend a vector?
Replies: 0
Views: 1096

bulk phase endocytosis

which of the following cells would you expect to be engaged most heavily in bulk-phase endocytosis a)an erythrocyte b)a pancreatic acinar c)a macrophage Why? I say it is macrophage, but I don't know why.

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by hannahzarzar
Sun May 22, 2011 4:26 am
 
Forum: Cell Biology
Topic: bulk phase endocytosis
Replies: 1
Views: 1497

More general biology questions..

... System 11. The lungs have surfactants, which as opsonins (substances that targets an antigen for an immune response) - is this true? 12. Are macrophages and phagocytes nautral killer cells? Wikipedia says that "NK cells are activated in response to interferons or macrophage-derived cytokines", ...

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by freedompeace
Fri Apr 15, 2011 12:30 pm
 
Forum: Cell Biology
Topic: More general biology questions..
Replies: 1
Views: 4124
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