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Macrolide

Macrolide

(Science: pharmacology) a group of antibiotics produced by various strains of streptomyces that have a complex macrocyclic structure.

They inhibit protein synthesis by blocking the 50S ribosomal subunit. Include erythromycin, carbomycin. Used clinically as broad spectrum antibiotics, particularly against gram-positive bacteria.


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kitasamycin is Belonging to the macrolide antibiotic

... developed by Japanese Kitasa Institute in 1960. The antibiotic was produced by Streptomycin kitasatoensis with the active compound of 16 carbon macrolide. The antibiotic has other names such as Selectomycin, leucomycin, ayermicina, sineptin. This antibiotic was approved by Ministry of ...

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by hinapharm
Sat Dec 15, 2007 4:23 am
 
Forum: Microbiology
Topic: kitasamycin is Belonging to the macrolide antibiotic
Replies: 0
Views: 4400

glandular fever and antibiotics

Just to add my 2 cents erythromycine belongs to the macrolide family, which has no cross resistance to the beta lactam family to which penicillin belongs. Erythromycine also stimulates non specific immunity and increase the number ofB and T lymphocyte. ...

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by canalon
Wed Jan 18, 2006 4:24 pm
 
Forum: Human Biology
Topic: glandular fever and antibiotics
Replies: 3
Views: 4039

Hmmm....differences between bacteria/eukaryote ribosomes?

... in Prokaryotes to stop tRNA binding. Aminoglycoside - Binds to the 30S unit of the prokaryote ribosome, mishapes it, and stops transcription. Macrolide - Binds to the 50S unit and stops mRNA movement in the ribosome. These are usually highly effective/broad spectrum anti-biotics. But a lot ...

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by EmmVeePee
Mon Jun 27, 2005 8:45 pm
 
Forum: Molecular Biology
Topic: Hmmm....differences between bacteria/eukaryote ribosomes?
Replies: 8
Views: 6989


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