Lymphocyte function-associated antigen-1

Lymphocyte function-associated antigen-1

a heterodimer molecule widely expressed on cells of haematopoietic origin. Cd11a antigen comprises the alpha chain and the cd18 antigen (antigens, cd18) the beta chain. Lfa-1 is a major receptor of T-cells, B-cells, and granulocytes. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper t-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes. Intracellular adhesion molecule-1 (icam-1) has been defined as a ligand for lfa-1.

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Specific memory in Innate Immune System

... to help after 96 hours, when there is still antigen within the body and innate immunity gives ... dendritic cells and macrophage switch their function from antigen-eating to become antigen-presenting. ... are active during adaptive immunity. Lymphocyte do nothing in innate immunity. Phagocytes ...

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by Dr.Stein: Fri Feb 10, 2006 9:55 am; Forum: Physiology; Topic: Specific memory in Innate Immune System; Replies: 42; Views: 18138

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Lymphocyte function-associated antigen-1

Results from our forum

Specific memory in Innate Immune System