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Lymph node

Lymph node

(Science: anatomy) small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells located along the lymphatic system.

Recirculating lymphocytes leave the blood through the specialised high endothelial venules of the lymph node and pass through the node before being returned to the blood through the lymphatic system. Because the lymph nodes act as drainage points for tissue fluids, they are also regions in which foreign antigens present in the tissue fluid are most likely to begin to elicit an immune response. Nodes filter Out bacteria or cancer cells that may travel through the lymphatic system.

Synonym: lymph glands. The source of lymph and lymphocytes.A type of tissue responsible for producing antibodies to fight antigens that is present in birds and mammals.

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tumor metastasis

... into the blood supply. They are swept around the body in the blood (and lymph) as CTCs (Circulating Tumour Cells), until they reach another organ ... to the primary in terms of blood supply. The concept of 'sentinel' nodes is similar - it's the lymph node closest to the drainage area from ...

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by Julie5
Sat Nov 06, 2010 1:58 pm
Forum: Cell Biology
Topic: tumor metastasis
Replies: 1
Views: 6186

African vs American immune systems

... by the immune cell (B or T), but it still has to drag it back to the lymph node and come up with an immune cell that bind to it tightly and begin to attack it aggressively ...

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by kolean
Sun Aug 29, 2010 3:11 pm
Forum: General Discussion
Topic: African vs American immune systems
Replies: 8
Views: 8197


... tissues including at the site of infection? Yes, the final stages of lymphocyte differentiation take place in the peripheral tissues. Often this peripheral tissue is a secondary lymphoid tissue, such as a lymph node, but also circulating naive CD45RA+ lymphocytes in the blood or at the ...

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by biohazard
Wed Apr 15, 2009 6:35 am
Forum: Human Biology
Topic: T cell differentiation
Replies: 16
Views: 35470

Bubonic plague - yersinia pestis info please

... ability to resist phagocytosis, and opsonization, and it resides in the lymph node areas as it grows, which creates the buboes. I can refer back to my book and give you ...

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by mathkilla
Sat Dec 15, 2007 6:57 am
Forum: Microbiology
Topic: Bubonic plague - yersinia pestis info please
Replies: 5
Views: 5762

Immunohistochemistry HELP--paraffin vs frozen sections

... getting the staining to show correctly. So far, I've been staining lymph node tissue for CD62L (L-selectin) and CD3, both of which are supposed to be quite abundant ...

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by wetheril
Fri Mar 30, 2007 8:48 pm
Forum: Molecular Biology
Topic: Immunohistochemistry HELP--paraffin vs frozen sections
Replies: 0
Views: 2764
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