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Ltr --> long-terminal repeat

(Science: molecular biology) identical dna sequences, several hundred nucleotides long, found at either end of transposons and the proviral dna, formed by reverse transcription of retroviral rna.

They are thought to have an essential role in integrating the transposon or provirus into the host dna. Long terminal repeats have inverted repeats, that is, sequences close to either end are identical when read in opposite directions. In proviruses the upstream long-terminal repeat acts as a promoter and enhancer and the downstream long-terminal repeat as a polyadenylation site.

Acronym: ltr

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5' LTR sequece

You may try to find comparable restriction endoneucleases for wild type 5'LTR. Hybrid 5'LTR generates different size RE digest products.

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by Helics
Fri Aug 01, 2014 6:07 pm
Forum: Molecular Biology
Topic: 5' LTR sequece
Replies: 1
Views: 259

5' LTR sequece

Hi, I want to check the 5' LTR sequence of my plasmid. I will like to confirm that it is a hybrid 5' LTR and not a wild type HIV-1 5' LTR. Can someone pls guide me on how I can evaluate this? Best, John

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by aguy
Mon Jul 07, 2014 10:02 pm
Forum: Molecular Biology
Topic: 5' LTR sequece
Replies: 1
Views: 259

dialogue for short film

... Neuralgia When I started the stochastic activation of CD4 T cells, the latency was overcome by the Tat-mediated transactivation of the LTR, so the virus gene transcription and production of infection-competent viral particles reconstituted the viral reservoir. Thanks a bunch!!

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by ricketybridge
Sat Jan 09, 2010 12:56 am
Forum: Microbiology
Topic: dialogue for short film
Replies: 4
Views: 3994

plant embryo

... by the continuous division of the zygote[which is a single cell]..so its a mass of cells, undifferentiated at the beginning and differentiates ltr..

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by vinaya
Thu May 17, 2007 7:43 am
Forum: Cell Biology
Topic: plant embryo
Replies: 5
Views: 2285

The Fiber Disease

... endogenous HERV-K progeny. We also show that this element amplifies via an extracellular pathway involving reinfection, at variance with the non-LTR-retrotransposons (LINEs SINEs) or LTR-retrotransposons, thus recapitulating ex vivo the molecular events responsible for its dissemination in the ...

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by London
Fri Dec 01, 2006 4:22 pm
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5414363
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