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Ltr

Ltr --> long-terminal repeat

(Science: molecular biology) identical dna sequences, several hundred nucleotides long, found at either end of transposons and the proviral dna, formed by reverse transcription of retroviral rna.

They are thought to have an essential role in integrating the transposon or provirus into the host dna. Long terminal repeats have inverted repeats, that is, sequences close to either end are identical when read in opposite directions. In proviruses the upstream long-terminal repeat acts as a promoter and enhancer and the downstream long-terminal repeat as a polyadenylation site.

Acronym: ltr


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Re: Locus specificity and ERVs - Q from a creationist

... argument fails if functional ERV genes do not need to be in specific locations in order to perform their functions. Unless we are talking about LTR promoters of native genes, this does seem to be the case. Re. locus targeting, see http://erv-faq-for-creationists.wikispaces.com/Don%27t+retroviruses+target+particular+locations+in+the+DNA%3F+Doesn%27t+this+explain+corresponding+ERVs%3F

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by BarryDesborough
Sat Aug 30, 2014 8:00 am
 
Forum: Genetics
Topic: Locus specificity and ERVs - Q from a creationist
Replies: 5
Views: 2097

5' LTR sequece

You may try to find comparable restriction endoneucleases for wild type 5'LTR. Hybrid 5'LTR generates different size RE digest products.

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by Helics
Fri Aug 01, 2014 6:07 pm
 
Forum: Molecular Biology
Topic: 5' LTR sequece
Replies: 1
Views: 375

5' LTR sequece

Hi, I want to check the 5' LTR sequence of my plasmid. I will like to confirm that it is a hybrid 5' LTR and not a wild type HIV-1 5' LTR. Can someone pls guide me on how I can evaluate this? Best, John

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by aguy
Mon Jul 07, 2014 10:02 pm
 
Forum: Molecular Biology
Topic: 5' LTR sequece
Replies: 1
Views: 375

dialogue for short film

... Neuralgia When I started the stochastic activation of CD4 T cells, the latency was overcome by the Tat-mediated transactivation of the LTR, so the virus gene transcription and production of infection-competent viral particles reconstituted the viral reservoir. Thanks a bunch!!

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by ricketybridge
Sat Jan 09, 2010 12:56 am
 
Forum: Microbiology
Topic: dialogue for short film
Replies: 4
Views: 4063

plant embryo

... by the continuous division of the zygote[which is a single cell]..so its a mass of cells, undifferentiated at the beginning and differentiates ltr..

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by vinaya
Thu May 17, 2007 7:43 am
 
Forum: Cell Biology
Topic: plant embryo
Replies: 5
Views: 2303
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