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Loops


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Why would the identical amino acids region of certain specie

... species which are somewhere diverse, somewhere are identical. For example the region coding for active site will be probably conserved, while some loops on surface of the protein will be divergent. Both on DNA and amino acid level. You can design primers on the divergent regions and then they will ...

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by JackBean
Mon Feb 18, 2013 3:51 pm
 
Forum: Genetics
Topic: Why would the identical amino acids region of certain specie
Replies: 2
Views: 185

Collect the cytoplasmic loop segments from 7TM receptors

You need to determine, which segments are membrane-spanning helices. The rest are the extra-membranous loops. What I remember about 7TM proteins, one of them should be considerably longer and that's the one you are looking for ;)

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by JackBean
Mon Apr 02, 2012 10:07 am
 
Forum: Bioinformatics
Topic: Collect the cytoplasmic loop segments from 7TM receptors
Replies: 1
Views: 1415

Collect the cytoplasmic loop segments from 7TM receptors

... I am asking for help/advice from any kind people who know more than me about that subject. My project objective is to find out whether cytoplasmic loops of '7-transmembrane helix' receptor proteins show structural homology/conserved features. I have chosen Class C (or 3) Metabotropic glutamate ...

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by studentbio
Mon Mar 19, 2012 6:00 pm
 
Forum: Bioinformatics
Topic: Collect the cytoplasmic loop segments from 7TM receptors
Replies: 1
Views: 1415

Re: Theories - Origin of Life

... study this paper about the regulation by and of p53 master sensor of stress. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857175/ Tied Up in Loops: Positive and Negative Autoregulation of p53 In part it states Of these, p53/mdm2 is the master autoregulation loop, and it dictates the fate ...

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by scottie
Wed Feb 22, 2012 8:12 pm
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 548
Views: 534596

Reasons for Skepticism on the Endosymbiosis?

... de Roos writes , [I]n linear mitochondrial chromosomes various different mechanisms to "prevent" shortening exist, ranging from hairpin loops and self-priming to protein-assisted primer synthesis (see here ). The telomeric regions of mitochondrial chromosomes do not seem to have a direct ...

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by SuperfluousAvatar
Thu Jan 12, 2012 7:43 pm
 
Forum: Cell Biology
Topic: Reasons for Skepticism on the Endosymbiosis?
Replies: 0
Views: 2616
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