Loops

... species which are somewhere diverse, somewhere are identical. For example the region coding for active site will be probably conserved, while some loops on surface of the protein will be divergent. Both on DNA and amino acid level. You can design primers on the divergent regions and then they will ...

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You need to determine, which segments are membrane-spanning helices. The rest are the extra-membranous loops. What I remember about 7TM proteins, one of them should be considerably longer and that's the one you are looking for ;)

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... I am asking for help/advice from any kind people who know more than me about that subject. My project objective is to find out whether cytoplasmic loops of '7-transmembrane helix' receptor proteins show structural homology/conserved features. I have chosen Class C (or 3) Metabotropic glutamate ...

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... study this paper about the regulation by and of p53 master sensor of stress. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857175/ Tied Up in Loops: Positive and Negative Autoregulation of p53 In part it states Of these, p53/mdm2 is the master autoregulation loop, and it dictates the fate ...

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... de Roos writes , [I]n linear mitochondrial chromosomes various different mechanisms to "prevent" shortening exist, ranging from hairpin loops and self-priming to protein-assisted primer synthesis (see here ). The telomeric regions of mitochondrial chromosomes do not seem to have a direct ...

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