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Dictionary » L » Locus

Locus

Definition

noun, plural: loci

(general) A place, space or locality, especially a centre of an activity.

(mathematics) The set of all points whose coordinates satisfy a given equation or condition.

(genetics) The location of a gene (or of a significant sequence) on a chromosome, as in genetic locus.

(medicine) The site on the body where a pathogen enters.


Supplement

Word origin: Latin stlocus, a place.

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Re: PCR

... two loci in any human (unless the primers are poorly chosen and so there is off-target binding due to allelic variation). So, you prime at the locus of the forward primer target and prime at the locus of the reverse primer target, but the distance between these two targets varies with the individual's ...

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by jonmoulton
Tue Jan 29, 2013 4:16 pm
 
Forum: Genetics
Topic: PCR
Replies: 2
Views: 502

Reporter gene without fusion

... same promoter just separate (e.g. both under control of bGlu promoter), than the expression should be similar, because it should be on the same locus with the same strenght etc. However, if you mean (and I do not think so) some completely different promoter than of course it won't be the same.

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by JackBean
Fri Jan 25, 2013 12:57 pm
 
Forum: Molecular Biology
Topic: Reporter gene without fusion
Replies: 1
Views: 248

parallel binding of miRNA with mRNA

if it's from the opposite strand, it must be antiparallel. If it's parallel, it must be transcribed either from the mRNA or from other locus.

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by JackBean
Sun Jan 20, 2013 5:39 pm
 
Forum: Genetics
Topic: parallel binding of miRNA with mRNA
Replies: 9
Views: 864

parallel binding of miRNA with mRNA

if they are transcribed from opposite strands (on the same locus of course) than they are complementary and can bind to each other just as the DNA strands do

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by JackBean
Thu Jan 17, 2013 8:38 am
 
Forum: Genetics
Topic: parallel binding of miRNA with mRNA
Replies: 9
Views: 864

Gene targeting

sir is it possible to remove a specific gene if its locus in the dna is known by gene targeting in humans ?

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by gauthum
Tue Dec 18, 2012 2:03 pm
 
Forum: General Discussion
Topic: Gene targeting
Replies: 12
Views: 1370
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