Dictionary » L » Locus

Locus

Definition

noun, plural: loci

(general) A place, space or locality, especially a centre of an activity.

(mathematics) The set of all points whose coordinates satisfy a given equation or condition.

(genetics) The location of a gene (or of a significant sequence) on a chromosome, as in genetic locus.

(medicine) The site on the body where a pathogen enters.


Supplement

Word origin: Latin stlocus, a place.

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I have got some BIG issues! forgive the long post

... are synthesized by a series of reactions; the A and B transferases encoded by the functional alleles (A and B alleles) of a single gene at the ABO locus, catalyze the last step of the synthesis, while the protein coded by the O allele is non-functional; therefore, the acceptor substrate, (H antigen) ...

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by saddy51
Sun Jan 04, 2015 10:39 am
 
Forum: Genetics
Topic: I have got some BIG issues! forgive the long post
Replies: 1
Views: 1906

Mutuation saturation at a particular locus

Hi guys, newbie here, but no less enthusiastic! Quick question in regards to mutation saturation at a locus... What is it in the context of comparing two lineages? I know that it occurs most in hyper-variable regions like in mitDNA, but what effect does this have on comparing ...

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by SimonNSmith
Fri Dec 19, 2014 8:43 pm
 
Forum: Evolution
Topic: Mutuation saturation at a particular locus
Replies: 0
Views: 496

Re: Locus specificity and ERVs - Q from a creationist

... locations in order to perform their functions. Unless we are talking about LTR promoters of native genes, this does seem to be the case. Re. locus targeting, see http://erv-faq-for-creationists.wikispaces.com/Don%27t+retroviruses+target+particular+locations+in+the+DNA%3F+Doesn%27t+this+explain+corresponding+ERVs%3F

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by BarryDesborough
Sat Aug 30, 2014 8:00 am
 
Forum: Genetics
Topic: Locus specificity and ERVs - Q from a creationist
Replies: 5
Views: 4338

Re: Locus specificity and ERVs - Q from a creationist

The reasoning fails if the adaptive functions do not depend on their exact loci. I don't really understand your reasoning. However, retroviruses are the major players and drivers of evolution. When they insert into host genome, they can alter host genes located at and around the insertion point - t...

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by Cat
Sun Sep 15, 2013 4:08 pm
 
Forum: Genetics
Topic: Locus specificity and ERVs - Q from a creationist
Replies: 5
Views: 4338

Locus specificity and ERVs - Q from a creationist

A question for geneticists - How essential is it that a gene or other section of DNA that performs a useful function is at a particular locus? I ask, because I am discussing endogenous retroviruses (ERVs) with an evolution-denier, who says that the ERVs that are apparently orthologous in, ...

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by BarryDesborough
Sat Sep 07, 2013 2:49 pm
 
Forum: Genetics
Topic: Locus specificity and ERVs - Q from a creationist
Replies: 5
Views: 4338
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