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Lo dose

Lo dose

(Science: pharmacology) The limes nul dose of diphtheria toxin, i.e., the largest amount of toxin that, when mixed with one unit of antitoxin and injected subcutaneously into a 250-g guinea pig, yields no recognizable reaction in the average of a series; actually, the Lod. Is usually recorded as the one that causes a barely perceptible local oedema at the site of inoculation.


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"dose"-response curves

I have always wondered why dose-response curves are constructed against the concentration of a drug rather than the amount of a drug. Typically, an effect increases or decreases with increasing concentration in g/l or mol/l. Why not graphing ...

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by Mathias
Wed Feb 25, 2015 3:23 pm
 
Forum: Cell Biology
Topic: "dose"-response curves
Replies: 0
Views: 323

Re: Human Collembola Infestations

... didn't bother to check my skin and just went on to prescribe ivermectin. By then I was going quiet nuts and took a slightly higher than necessary dose of ivermectin. The next day I thought I was dying along with the bugs inside of me. I had to FORCE myself to breathe, my central nervous system ...

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by sammygirl
Thu Feb 05, 2015 2:16 pm
 
Forum: Human Biology
Topic: Human Collembola Infestations
Replies: 47
Views: 133186

Human Collembola Infestations

... used by ~6 million people world-wide and no known dangerous side effects. I didn't have ANY. Just relief. Make sure not to delay the follow-up dose too long; otherwise the arthropod will have time to mature and reproduce more eggs. Then the whole cycle starts over.

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by urthchik
Mon Oct 06, 2014 6:38 pm
 
Forum: Human Biology
Topic: Human Collembola Infestations
Replies: 47
Views: 133186

Human Collembola Infestations

... should NOT be done for parasitic infections because it lowers immunity and allows them to propagate uninhibited. I finally took ivermectin in 2 doses. The first dose slowed it down but the itching returned within a few days. My guess is that the next hatching of eggs occurred and they are impervious ...

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by urthchik
Sun Oct 05, 2014 12:20 am
 
Forum: Human Biology
Topic: Human Collembola Infestations
Replies: 47
Views: 133186

Re: Any ideas for vaccine development or anti-viral drugs???

... P-PMO designed to base pair with the translation start site region of EBOV VP35 positive-sense RNA generated sequence-specific and time- and dose-dependent inhibition of EBOV amplification in cell culture. The same oligomer provided complete protection to mice when administered before or ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 12822
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