Dictionary » L » Lipopolysaccharide

Lipopolysaccharide

Definition

noun, plural: lipopolysaccharides

A compound in which a lipid molecule is bound to a polysaccharide by a covalent bond.


Supplement

Lipopolysaccharide is commonly found as major constituent of the cell walls of certain bacteria, particularly the gram-negative strains, whose function is to help stabilize the overall membrane structure and to protect it from certain chemicals.

It is highly immunogenic and stimulates the production of endogenous pyrogen interleukin-1 and tumour necrosis factor. It is a potent activator of macrophages.


Word origin: from Greek lĂ­pos, fat + polysaccharide.

Abbreviation: LPS
See also: lipid a.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Which is more dangerous, gram-positive or gram-negative?

Well, as long as I know, most gram-negative bacteria are pathogens. According to their cell wall structure which has the Lipopolysaccharides on top of its outer membrane. Lipopolysaccharide is toxic chemical for human. You may use this reason to say that gram-negative bacteria have ...

See entire post
by pratumchai
Tue Aug 12, 2008 8:30 am
 
Forum: Cell Biology
Topic: Which is more dangerous, gram-positive or gram-negative?
Replies: 1
Views: 9887

The Fiber Disease

Important article: Cyanobacterial lipopolysaccharide/s (LPS) are frequently cited in the cyanobacteria literature as toxins responsible for a variety of health effects in humans, from skin rashes to gastrointestinal, respiratory and allergic ...

See entire post
by tamtam
Tue Dec 12, 2006 2:35 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 4988623

The Fiber Disease

... from pigs with postweaning diarrhoea were examined by PCR for the presence of the O157 rfb gene responsible for the biosynthesis of E coli O157 lipopolysaccharide. Among the 372 isolates tested, 38 (10.2 per cent) were of the O157 serogroup, but none of these possessed the H7 determinant. Further ...

See entire post
by London
Thu Nov 16, 2006 11:59 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 4988623

The Fiber Disease

... bacteria (54, 55), which may also play a significant role in stimulating immune responses in the infected host such as the cell-wall-associated lipopolysaccharide and peptidoglycan. this herbicide, were found closely positioned in the genome. In addition, ORFs for the synthesis of medically ...

See entire post
by Beth
Mon Oct 09, 2006 9:49 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 4988623

The Fiber Disease

... called porins in gram-negative bacteria like E. coli [79, 80] and other surface proteins such as Staphylococcal protein A [81] or endotoxin (lipopolysaccharide or LPS), a variable-size carbohydrate chain that is the major antigen of the outer membrane of gram-negative bacteria. Mycobacteria ...

See entire post
by Nadas Moksha
Mon Sep 11, 2006 2:05 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 4988623
View all matching forum results

This page was last modified 06:45, 12 August 2008. This page has been accessed 25,741 times. 
What links here | Related changes | Permanent link