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Linkage marker

Linkage marker

a locus at which there is a high probability of heterozygotes (indispensible state for linkage analysis), but in itself perhaps of no clinical interest.

See: marker locus.


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linkage disequlibrium, haplotypes, SNPs

hello I am a little bit confused about the relationship between LD, haplotypes and SNPs. Is that correct? SNPs act as markers, they may be in LD with the susceptibility alleles for a disease. Generally, SNPs together with other genetic variants (like disease alleles) can be inherited ...

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by tou
Thu Apr 21, 2011 12:11 am
 
Forum: Genetics
Topic: linkage disequlibrium, haplotypes, SNPs
Replies: 1
Views: 1766

Re:

... HWE, does this mean that this gene cannot be used as a genetic marker or there is no hope for this Loci to be in Linkage-disequilibrium with any other gene Maybe the gene can be in a linkage.. But does HW ...

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by F4T32008
Sun May 11, 2008 4:23 pm
 
Forum: Genetics
Topic: About Pop. genetic heterozygosity & HWE
Replies: 4
Views: 4939

About Pop. genetic heterozygosity & HWE

... HWE, does this mean that this gene cannot be used as a genetic marker or there is no hope for this Loci to be in Linkage-disequilibrium with any other gene i think this is enough for now if anyone have a ...

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by Proteinic
Tue May 06, 2008 3:41 pm
 
Forum: Genetics
Topic: About Pop. genetic heterozygosity & HWE
Replies: 4
Views: 4939

Linkage disequilibrium

Linkage is established when a certain genetic marker (say a RFLP or a SNP), ie a genotypic trait, is inherited consistently through generations in a family together ...

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by weesper
Sat May 05, 2007 9:13 pm
 
Forum: Molecular Biology
Topic: Linkage disequilibrium
Replies: 1
Views: 1307

Genetic maps

linkage analysis is one of the first steps... it can give you a good idea of what arm of what ... once you know that ... you can then see if "your favorite gene" segregates with markers (on the chromosome of the arm that you've already identified)... and once you figure ...

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by LilKim
Mon May 15, 2006 10:05 pm
 
Forum: Genetics
Topic: Genetic maps
Replies: 5
Views: 2476


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