Ligands

In Systematic evolution of Ligands by Exponential Enrichment a resin column attached with ATP is used for desired ligand development . This ATP give the desire ligand a property for binding tightly with ATP. Should we used any other drug ?

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bi- and bis- means the same. Bi- is used for smaller ligands, while bis- is for larger ligands.

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... these don't seem to match the diagrams. I'd like to find pdb structures to illustrate how hexokinase conforms to bind ATP and glucose, with the ligands enclosed inside the molecule. I'd be grateful for any help.

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... of the body than before. I'm not aware of significant "chemical" synthesis of antibodies - though certainly of associated therapeutic ligands. Can you say more?

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1. of course you can use both, but their are kind of complementary. In the first case you have database of millions of possible ligands and try them all on your protein. In the other case, you have structure of your protein and determines the minimum, which binds into it. Then you try ...

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