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Ligands

Ligands

a molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex.


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High-throughput protein-structure determination

... have one protein(P)-ligand(L) complex structure, you can also get easily( high-throughput ) other complex structures that same protein bound other ligands. P-L1 complex enables you to get P-L2 complex, P-L3 complex, P-L4 complex, and so on. Please teach me any information. Thank you. :D

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by syrup16g
Tue Nov 18, 2014 11:35 am
 
Forum: Molecular Biology
Topic: High-throughput protein-structure determination
Replies: 1
Views: 564

SELEX

In Systematic evolution of Ligands by Exponential Enrichment a resin column attached with ATP is used for desired ligand development . This ATP give the desire ligand a property for binding tightly with ATP. Should we used any other drug ?

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by Helics
Thu Feb 07, 2013 4:09 pm
 
Forum: Molecular Biology
Topic: SELEX
Replies: 3
Views: 2157

can some one tell what rubp stands for ?

bi- and bis- means the same. Bi- is used for smaller ligands, while bis- is for larger ligands.

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by JackBean
Sat Nov 10, 2012 11:18 am
 
Forum: Molecular Biology
Topic: can some one tell what rubp stands for ?
Replies: 7
Views: 3391

hexokinase conformation

... these don't seem to match the diagrams. I'd like to find pdb structures to illustrate how hexokinase conforms to bind ATP and glucose, with the ligands enclosed inside the molecule. I'd be grateful for any help.

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by andrewJM
Sat Jul 21, 2012 4:45 pm
 
Forum: Molecular Biology
Topic: hexokinase conformation
Replies: 0
Views: 1643

antibiotics vs antibacterial drugs..

... of the body than before. I'm not aware of significant "chemical" synthesis of antibodies - though certainly of associated therapeutic ligands. Can you say more?

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by JorgeLobo
Wed Mar 28, 2012 11:49 am
 
Forum: Microbiology
Topic: antibiotics vs antibacterial drugs..
Replies: 4
Views: 7723
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