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Ligand gated ion channels

Ligand gated ion channel

a transmembrane ion channel whose permeability is increased by the binding of a specific ligand, typically a neurotransmitter at a chemical synapse. The permeability change is often drastic, such channels let through effectively no ions when shut, but allow passage at up to 10exp7 ions sexp 1 when a ligand is bound. Recently, the receptors for both acetylcholine and gaba have been found to share considerable sequence homology, implying that there may be a family of structurally related ligand gated ion channels.

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Re: Muscle Contractions

... Ach binds to its nicotinic receptor, it opens ligand gated channels for Na+ diffusion into muscular cell. This gives it enough ...

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by Jpoley
Tue Mar 01, 2011 2:42 am
Forum: Human Biology
Topic: Muscle Contractions
Replies: 1
Views: 7828

Insulin signaling

... and travels thru out the body. Insulin is a ligand for the insulin receptors that are found ... system in which the cell then can open the gated channels and let more than the normal passage of glucose ...

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by kolean
Thu Aug 20, 2009 2:58 am
Forum: Human Biology
Topic: Insulin signaling
Replies: 1
Views: 4445

Simple Diffusion`

Movement of O2 is not simple diffusion? so what is it? The movement is ... Ionotropic receptors are ligand-gated ion channels that open or close through neurotransmitter ...

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by Poison
Fri Apr 21, 2006 11:09 pm
Forum: Cell Biology
Topic: Simple Diffusion`
Replies: 7
Views: 17413

nervous system

... and then propagating action potentials. Once stimulated and ... an action potential is propagated through the depolarization of ... of sodium and potassium specific ligand gated ion channels on the plasma membrane of the ...

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by nabizko
Thu Nov 24, 2005 9:01 am
Forum: Human Biology
Topic: nervous system
Replies: 6
Views: 3454

cellular signalling

... something up on the activation of genes by extra-cellular signalling ... what about G-protein receptors or ligand ion gated channels? these aswell?

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by lollipop29
Sat Sep 03, 2005 4:47 am
Forum: Cell Biology
Topic: The Living Cell
Replies: 7
Views: 6381

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