Home Forum Dictionary Articles Tutorials Books Directory Share your work


Edit page | Page history | Printable version

Dictionary » L » Ligand

Ligand

Definition

noun, plural: ligands

(1) A molecule, ion or atom bonded to the central metal atom of a coordination compound.

(2) Any substance (e.g. hormone, drug, functional group, etc.) that binds specifically and reversibly to another chemical entity to form a larger complex.


Supplement

A ligand may function as agonist or antagonist.

Many ligands are found in biological systems, such as cofactors and porphyrin in hemoglobin.


Word origin: From Latin ligandus, gerundive of ligare ‘to bind’.

Related term: ligand gated ion channels


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


SELEX

You can use any ligand you want. For applications look up PubMed.

See entire post
by JackBean
Sat Feb 09, 2013 5:39 pm
 
Forum: Molecular Biology
Topic: SELEX
Replies: 3
Views: 331

SELEX

In Systematic evolution of Ligands by Exponential Enrichment a resin column attached with ATP is used for desired ligand development . This ATP give the desire ligand a property for binding tightly with ATP. Should we used any other drug ?

See entire post
by Helics
Thu Feb 07, 2013 4:09 pm
 
Forum: Molecular Biology
Topic: SELEX
Replies: 3
Views: 331

Intrinsic apoptosis in erythrocytes

... of generating cytochrome c to attach to a CARD domain and assemble the apoptosome? Or are they dependent on killer lymphocytes to bind via the fas ligand and activate procaspase 8 or 10 in extrinsic apoptosis? Do red blood cells even have fas ligand receptors for this process? Or is there an entirely ...

See entire post
by billyfisher100
Fri Apr 27, 2012 10:04 pm
 
Forum: Cell Biology
Topic: Intrinsic apoptosis in erythrocytes
Replies: 3
Views: 1806

Did learning this make you guys atheists?

... a gene encoding, say, a protein for converting chemical X into Y, and then just removing one nucleotide results in the protein, say, acting as a ligand and telling drosophila melanogaster to grow legs on the head rather than on the body. Anyone else have similar stories?

See entire post
by yodachoda87
Thu Mar 15, 2012 1:44 am
 
Forum: Genetics
Topic: Did learning this make you guys atheists?
Replies: 0
Views: 798

Dilution problem

... tried two methods. I understand how to to dilutions, trust me, but to get this numbers to work is another story. Help will be much appreciated! Ligand X stock: 100 ug/mL ( there's a total of 1 mL of the stock. but we have less than that now. ) [ Method 1 ] I want to dilute 100 ug/mL to 10 ug/mL. ...

See entire post
by daphnis
Wed Jan 25, 2012 5:56 am
 
Forum: Molecular Biology
Topic: Dilution problem
Replies: 1
Views: 742
View all matching forum results

This page was last modified 00:30, 22 March 2009. This page has been accessed 69,063 times. 
What links here | Related changes | Permanent link