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Lethal mutation

Definition

noun

A type of mutation in which the effect(s) can result in the death or reduce significantly the expected longevity of an organism carrying the mutation.


Supplement

For instance, brachydactyly is a fatal when the genetic defect is expressed during infancy in homozygous recessive individuals.


Compare: nonlethal mutation


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mutation-selection balance

... in death before the person can reproduce. This is termed a genetic lethal mutation because, even though the individual might survive for some time, he or she contributes ...

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by Monco
Mon Mar 04, 2013 10:41 pm
 
Forum: Genetics
Topic: mutation-selection balance
Replies: 0
Views: 3264

Synthetitic genetic screening in yeast

... for purposes of analogy also equate being unable to access the car with lethal phenotype (as car is useless). Now, in this situation you need to ... (like loss of a key in the above example) and then look for the other mutation that would result in lethal phenotype when combined with it. It ...

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by Cat
Mon Sep 10, 2012 6:51 pm
 
Forum: Molecular Biology
Topic: Synthetitic genetic screening in yeast
Replies: 4
Views: 3430

Re: Re:

Rap: DNA does not evolve into mutation-resistant. Simply if the mutation would be lethal then nothing with mutated DNA survives thus it seems like mutation resistant. Also, the identical ...

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by JackBean
Mon Sep 10, 2012 3:08 pm
 
Forum: Evolution
Topic: Increasing Information For Genetic Algorithm
Replies: 8
Views: 12661

Re:

Rap: DNA does not evolve into mutation-resistant. Simply if the mutation would be lethal then nothing with mutated DNA survives thus it seems like mutation resistant. Also, the identical ...

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by Rap
Thu Sep 06, 2012 1:54 am
 
Forum: Evolution
Topic: Increasing Information For Genetic Algorithm
Replies: 8
Views: 12661

Increasing Information For Genetic Algorithm

Rap: DNA does not evolve into mutation-resistant. Simply if the mutation would be lethal then nothing with mutated DNA survives thus it seems like mutation resistant. Also, the identical ...

See entire post
by JackBean
Tue Sep 04, 2012 2:06 pm
 
Forum: Evolution
Topic: Increasing Information For Genetic Algorithm
Replies: 8
Views: 12661
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