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Lethal Gene

Any gene that has an effect that causes the death of the organism at any stage of life.A genes whose effect on the phenotype is profoundly negative, and causes the organism to exhibit many disadvantageous characteristics, which can eventually lead to death.lethal gene

a gene that produces a genotype that leads to death of the organism before reproduction is possible or that precludes reproduction; for a recessive gene the homozygous or hemizygous state is lethal.

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Re: Any ideas for vaccine development or anti-viral drugs???

... VP35 Knockdown Inhibits Ebola Virus Amplification and Protects against Lethal Infection in Mice. Antimicrob Agents Chemother. 2006 Mar;50(3):984-93. ... DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S. Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 12524

mutation-selection balance

... that results in death before the person can reproduce. This is termed a genetic lethal mutation because, even though the individual might survive for some time, he or she ...

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by Monco
Mon Mar 04, 2013 10:41 pm
Forum: Genetics
Topic: mutation-selection balance
Replies: 0
Views: 4031

Synthetitic genetic screening in yeast

... for purposes of analogy also equate being unable to access the car with lethal phenotype (as car is useless). Now, in this situation you need to ... to get "lethal" phenotype... People create mutants in one gene with mild phenotype (like loss of a key in the above example) and then ...

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by Cat
Mon Sep 10, 2012 6:51 pm
Forum: Molecular Biology
Topic: Synthetitic genetic screening in yeast
Replies: 4
Views: 4339

Re: Theories - Origin of Life

... symptoms. They still make sickle-shaped cells, but those cells generally do not cause them problems.You're right to say that I'm simplifying ... only cares about reproduction, so a few individuals experiencing non-lethal symptoms will not outweigh the benefit of being malaria-resistant. ...

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by Luxorien
Thu Mar 08, 2012 10:21 pm
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 563
Views: 1127367

Re: Re:

... we can say "Repairable", "Un repairable" and "Lethal" Mutations. 6 finger mutation ( http://en.wikipedia.org/wiki/Polydactyly ... human behavior. How? Just think what will happen to the polydactyly genes in a person if he doesn't get married just because ...

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by christianstrategies
Tue Feb 07, 2012 7:10 pm
Forum: Evolution
Topic: Any SOLID arguments against evolution?
Replies: 309
Views: 591869
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