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Lethal

Lethal

deadly, fatal.

Origin: L. Lethalis, from lethum = death Of an instrument of certain death; deadly poisons; lethal weapon; a lethal injection.Of deadly proportions.


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Population genetics - make inferences from allele frequency

... populations across a whole species distribution is 0.75 or 0.5, can you make any inference about something like dominant-recessive relationship or lethal homozygotes? I assume random mating (no sexual selection), diploid, no drift (genetically well connected) or something that meets Hardy-Weinberg ...

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by Young
Sun Aug 25, 2013 10:52 pm
 
Forum: Genetics
Topic: Population genetics - make inferences from allele frequency
Replies: 1
Views: 1269

mutation-selection balance

... Carey and Bamshad: Consider, for example, a dominant disease that results in death before the person can reproduce. This is termed a genetic lethal mutation because, even though the individual might survive for some time, he or she contributes no genes to the next generation. Each time mutation ...

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by Monco
Mon Mar 04, 2013 10:41 pm
 
Forum: Genetics
Topic: mutation-selection balance
Replies: 0
Views: 3186

Re: mutations and dependencies

... these parts is very likely to disturb fatally the whole machinery; for this reason we should expect very many, if not most, mutations to result in lethal factors …” (Muller, H. J. (1918) “Genetic variability, twin hybrids and constant hybrids, in a case of balanced lethal factors.” Genetics 3:422-499. ...

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by wildfunguy
Sun Feb 17, 2013 8:33 pm
 
Forum: Evolution
Topic: mutations and dependencies
Replies: 29
Views: 20636

Synthetitic genetic screening in yeast

... into a car but not drive it (let's call it a different phenotype). Let's for purposes of analogy also equate being unable to access the car with lethal phenotype (as car is useless). Now, in this situation you need to lose BOTH key and alarm button to get "lethal" phenotype... People ...

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by Cat
Mon Sep 10, 2012 6:51 pm
 
Forum: Molecular Biology
Topic: Synthetitic genetic screening in yeast
Replies: 4
Views: 3327

Re: Re:

Rap: DNA does not evolve into mutation-resistant. Simply if the mutation would be lethal then nothing with mutated DNA survives thus it seems like mutation resistant. Also, the identical DNA strains have identical geometry (whatever that should mean) and, at least ...

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by JackBean
Mon Sep 10, 2012 3:08 pm
 
Forum: Evolution
Topic: Increasing Information For Genetic Algorithm
Replies: 8
Views: 12361
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