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Lectin

Lectin

(Science: plant biology) proteins obtained particularly from the seeds of leguminous plants, but also from many other plant and animal sources, that have binding sites for specific mono or oligosaccharides in cell walls or membranes. They thereby change the physiology of the membrane to cause agglutination, mitosis, or other biochemical changes in the cell.

Named originally for the ability of some to selectively agglutinate human red blood cells of particular blood groups. Lectins such as concanavalin a and wheat germ agglutinin are widely used as analytical and preparative agents in the study of glycoproteins.


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The Immune System - Recognition in innate immunity. How?

... complex mechanisms of recombination and mutation. The components of the innate immunity (e.g. Toll-like receptor on macrophages, mannose-binding lectin in the plasma) have their specificity encoded on a genomic level, are expressed in similar form on the surface of every cell of a given type, ...

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by biohazard
Tue May 12, 2009 7:43 am
 
Forum: Cell Biology
Topic: The Immune System - Recognition in innate immunity. How?
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Views: 1272

What does hemagglutination look like?

Hi. I'm a PhD student and I've been doing hemagglutination experiments to detect lectin activity in my samples (solubalised cells froma toxic species). My samples lyse live blood cells so I've been using fixed cells (I've fixed them myself). But the fixed cells ...

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by Lornadoon
Thu May 29, 2008 3:59 pm
 
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Topic: What does hemagglutination look like?
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lectin

Hi there, are lectin receptors in the rat intestine found mostly in the submucosa layer? anyone know? it also says where in the cell does most staining occur--does this mean like what organelle? thanks in advance biology_06er

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by biology_06er
Tue Aug 07, 2007 7:08 am
 
Forum: General Discussion
Topic: lectin
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The Fiber Disease

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by msc
Mon Dec 04, 2006 12:44 am
 
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Topic: The Fiber Disease
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The Fiber Disease

... glycoprotein, asialofetuin, and anti-RTB antibodies confirmed the characteristic type II ribosome-inactivating protein galactose binding lectin activity of the recombinant ricin. The enzymatic activity of recombinant ricin was characterized for cell-free translation inhibition, as well ...

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by London
Sat Nov 04, 2006 3:26 am
 
Forum: Human Biology
Topic: The Fiber Disease
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