Dictionary » L » Leader sequence

Leader sequence

Definition

noun

(1) 5' UTR (five prime untranslated region); the section of mRNA and DNA beginning at the +1 position up to that region prior to codon sequence, and transcribed into the ribosome-binding site

(2) Signal sequence


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Reasons for Skepticism on the Endosymbiosis?

... the mitochondria to the nucleus they would have to somehow pick up the leader sequences necessary to signal for transport before they could be functional. While leader sequences ...

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by SuperfluousAvatar
Thu Jan 12, 2012 7:43 pm
 
Forum: Cell Biology
Topic: Reasons for Skepticism on the Endosymbiosis?
Replies: 0
Views: 4820

CTLA-4

... gene consists of four exons. I read that the first exon contains the leader peptide sequence....but what does the leader peptide do? Signal peptide is in the beginning of the ...

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by ele
Wed Jan 13, 2010 11:42 am
 
Forum: Genetics
Topic: CTLA-4
Replies: 1
Views: 1040

which structure prevent site-specific recombination?

... nonsense, as the recombination takes place on DNA ;) B is just some sequence, so that shouldn't influence recombination. On the other hand, there are some proteins bound all the time, so maybe... C is my leader D this is just some repeating sequence, so why should you recombine that?

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by JackBean
Sun Dec 20, 2009 1:05 pm
 
Forum: Genetics
Topic: which structure prevent site-specific recombination?
Replies: 1
Views: 742

Protein Trafficking in cell

... location is the ER. What would happen if i removed the N-terminus leader sequence which is recongised by the SRP but left on the C-terminus KDEL sequence?? would the ...

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by drairways
Sun Oct 25, 2009 8:43 pm
 
Forum: Cell Biology
Topic: Protein Trafficking in cell
Replies: 2
Views: 1174

Re: is it possible to knockdown a gene in a living adult now

... works. They discuss the regulatory problems of having many different sequences needed to treat many different people each with their own unique ... therapeutic molecules on an individualized basis. Eric Hoffman, a leader in DMD research, published an interesting article relevant to this ...

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by jonmoulton
Fri Dec 05, 2008 8:41 pm
 
Forum: Genetics
Topic: is it possible to knockdown a gene in a living adult now
Replies: 10
Views: 13284
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