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Lead sequence

Definition

noun

Signal sequence, the sequence comprised of amino acid residues that guides the growing protein as to where it is destined to go within the cell through the transport mechanism that recognize this "lead" or "guide"


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Nucleotide Database

PubMed Contains only about 500 nucleotide sequences related to Hibiscus http://www.ncbi.nlm.nih.gov/nuccore?term=%22Hibiscus%22[Organism]&cmd=DetailsSearch ... probably end up with will be DNA library and degenerated probe, which will lead you to putative apetala gene from Hibiscus. After sequencing ...

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by JackBean
Tue Sep 25, 2012 9:19 am
 
Forum: Molecular Biology
Topic: Nucleotide Database
Replies: 9
Views: 3515

Nucleotide Database

... design a good primer for isolating my target genes..unfortunately the sequence references are very limited..most of the database lead me to arabidopsis..n i dont want to only use arabidopsis..i wanna isolate apetala genes ...

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by elynn
Wed Sep 19, 2012 1:59 pm
 
Forum: Molecular Biology
Topic: Nucleotide Database
Replies: 9
Views: 3515

cancers, chromosome mutations

I heard that a gene mutation can lead to cancers through the change of the base sequence of a gene that codes for certain protein, which are crucial for the regulation of cancer. But ...

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by biologyisgreat
Fri Jul 27, 2012 5:14 pm
 
Forum: Genetics
Topic: cancers, chromosome mutations
Replies: 6
Views: 6247

Molecular gene (genome) concept scientifically untenable

... into different tissue. Perhaps it is the presence of cofactors that lead to cell differentiation. Perhaps diffusion rates depletes the concentration ... Two hundred years ago, we did not know about bacteria. Now we have sequenced the genomes from many bacteria. One hundred years ago, we did not ...

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by DougB
Thu May 03, 2012 2:48 pm
 
Forum: Molecular Biology
Topic: Molecular gene (genome) concept scientifically untenable
Replies: 12
Views: 28014

Molecular gene (genome) concept scientifically untenable

... views of gene function strengthened the idea of genetic specificity leading to molecularization of the gene. In the early 1940s, Oswald Avery ... process of protein biosynthesis led to the idea that it was the linear sequence of ribonucleic acid derived from one of the DNA strands that directed ...

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by PAWahid
Wed May 02, 2012 4:54 am
 
Forum: Molecular Biology
Topic: Molecular gene (genome) concept scientifically untenable
Replies: 12
Views: 28014
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