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Latex agglutination

Latex agglutination

also known as latex particle agglutination, for detection of antibodies is identical to haemagglutination in principle, but the substitution of smaller, antigen-coated latex particles for erythrocytes results in improved sensitivity and reagent longevity. Alternatively, antibodies can be absorbed to the latex particles (under appropriate ionic and ph conditions) by binding to the fc region of antibodies, leaving the fab region free to interact with antigens present in the applied specimens. This phenomenon has made latex agglutination a popular technique for detecting antigens as well.

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Re: Staphyltect test mechanism

... linking IgG antibodies onto the surface of some kind of particles, e.g. latex beads. This allows one "antibody bead" to bind together much ... and while doing that also other such particles - this in turn forms agglutination visible by naked eye. Sole IgG antibodies are relatively weakly ...

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by biohazard
Tue Jan 22, 2008 7:48 am
Forum: Microbiology
Topic: Staphyltect test mechanism
Replies: 2
Views: 2420

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