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Laminin

Definition

noun

A trimeric glycoprotein comprised of an alpha-chain (about 400 kD) and two beta-chains (200 kD) (or an alpha-, beta- and gamma-chains), located in the basal lamina of connective tissues.


Supplement

Laminin was first studied from mouse EHS cells. Later, various forms of laminin were found.

Laminins are involved in many important biological processes such as cell differentiation, migration and adhesion.


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An Overview of Embryonic Stem Cells

... cells are also unresponsive to LIF and require culture on MEF feeder layers in the presence of basic fibroblast growth factor , or on matrigel or laminin in MEF-conditioned medium. The demonstration of pluripotency for murine ES cells usually involves reconstitution of embryos and the generation ...

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by 2444256703
Thu Jan 29, 2015 6:48 am
 
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nuclear lamina

... can refer to more than one structure. see here: http://en.wikipedia.org/wiki/Lamina lamins: intermediate filaments that make up the nuclear lamina laminin: protein that makes up the basal lamina of epithelial tissues.

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by MrMistery
Fri Nov 23, 2007 1:00 pm
 
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nuclear lamina

hi, i am confused with the word lumen, lamina, lamins and laminin etc. can anyone explain please?

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by gumshoes_15
Fri Nov 23, 2007 1:07 am
 
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... quite. the nuclear lamina has a main function of maintaing the shape of the nucleus. it is composed of an intermediate cytoskeletal protein named laminin.

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Wed Oct 10, 2007 12:17 pm
 
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