Kinases

Hi there, Was going through a past test questions and need some help with the following question: The glycine rich loop of protein kinases contains highly conserved glycine residues. Why are they conserved? possible info?? Glycine is flexible therefore allows loop to open up to phosphorylate ...

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... between all the members of this site. So... Do you think cell constant creatures can develop cancer? Now I thought about Cdks (cyclin dependent kinases) controlling the cell cycle, but could cancer stop that? I also thought about the protein p27, which inhibits the cell cycle. Does anyone know ...

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... of AMP and most certainly doesn’t generate a high-energy source like ATP. All the other reactions are possible via nucleotide and dinucleotide kinases. These kinase reactions are reversible.

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... by the action of glycogen phosphorylase. The activity of this enzyme is regulated by its of phosphorylation state by a series of kinases/dephosphorylases ultimately connected to – among other things, but primarily adrenergic and hormone receptors and cyclic-AMP (not to be confused ...

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... cell lines? I wish to find out if any of the following transcription factors/enzymes: pRb, P53, Mdm2, p21, p16 INK, p27, E2F-1 to 3, ATM/ATR, Chk kinases, CDK's, p300/pCAF, Arf, etc etc, are not expressed (or overexpressed) in the following cancer cell lines: MCF7, T98G, U2OS, U937, WI-38, AT3 ...

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