Dictionary » K » Kinase ii

Kinase ii

Kinase ii --> peptidyl-dipeptidase a

(Science: enzyme) a hydrolase cleaving C-terminal dipeptides from a variety of substrates, including angiotensin i, which is converted to angiotensin ii and histidylleucine.

An important step in the metabolism of certain vasopressor agents.

It is a chloride-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral ph. Only single dipeptides are released from angiotensin i and bradykinin because of the lack of activity on bonds involving proline. It may also have endopeptidase activity on some substrates.

registry number: EC 3.4.15.1

Synonym: carboxycathepsin, dipeptidyl carboxypeptidase, kinase ii, peptidase P.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


BRC-ALT Tyrosine Kinase

Does anyone know if the BRC-ALT tyrosine Kinase is a problem in leukemia because it is transcribed more often when on Chromosome 22 or if it is simply just always in the active configuration due the mutation, or both? I have looked on access ...

See entire post
by tmbirkhead
Thu Aug 14, 2014 1:22 am
 
Forum: Molecular Biology
Topic: BRC-ALT Tyrosine Kinase
Replies: 0
Views: 105

Cell signalling inhibitors

... for me some cell signalling inhibitors for C. elegans (or generic) and tell me the enzyme or receptor that is inhibited? (Preferably for tyrosine kinase, G-protein, JAK/STAT and Phosphatidylinositol 3-kinase) Thanks :D

See entire post
by billyfisher100
Wed Jan 08, 2014 7:35 pm
 
Forum: Cell Biology
Topic: Cell signalling inhibitors
Replies: 1
Views: 1456

Re:

... another textbook and you were right! Unlike what I first thought, glycolysis can't take place once glycogenolysis has started because the pyruvate kinase is inhibited by glucagon and adrenaline, so PEP can't turn into pyruvate anymore. Which is only adding to my confusion...

See entire post
by Aymeric
Sat Dec 14, 2013 11:51 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 5656

Re:

... which quickly is not the case anymore as soon as physical activity starts, right? And it is also activated by calcium (through the phosphorylase kinase) due to muscle contraction. Or am I mixing everything up?

See entire post
by Aymeric
Fri Dec 13, 2013 2:46 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 5656

MOLECULAR CLONING

... have 5'-OH and 3'-phosphate ends... DNA ligase removes 3'-phosphates and replaces it with -OH. Thus, synthesized oligos without polynucleotide kinase treatment will participate in the ligation reaction with both their ends having -OH groups. The 3'-OH end of the oligo will form covalent bond ...

See entire post
by kk
Fri Jul 19, 2013 12:50 pm
 
Forum: Molecular Biology
Topic: MOLECULAR CLONING
Replies: 9
Views: 5276
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 1,038 times. 
What links here | Related changes | Permanent link