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Definition

noun

(1) A type of T cell that does not express markers of either T or B-cell lineage, but may possess fc receptors for immunoglobulin g. It functions by killing target cell through antibody-dependent cell-mediated cytotoxicity or through perforin, killing cells without prior sensitization (hence, the name).

(2) Mammalian cell that is capable of lysing antibody-coated target cell.

Supplement

This type of cell attacks tumor cells and infected cells by releasing chemicals that are toxic to the cell, resulting to cell death of the target cell.

Variants:

• killer T cell
• natural killer cell