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Ketoconazole

Ketoconazole

(Science: drug) An antifungal medication available in pill and liquid form that is effective against a variety of fungal infections such as oral, vaginal and oesophageal thrush and cryptococcosis.

possible side effects include serious liver damage and reduced testosterone levels.


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Inhibition of enzyme - will it result in upregulation?

Hey all, I am trying to figure out a mystery here. In an experiment that I've done a few weeks ago, ketoconazole (CYP inhibitor) seems to result in an overall increase in the quantity of the CYP 450 proteins in the liver. I can understand how this works if it is a CYP inducer, ...

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by Jamus
Sat Apr 25, 2009 12:49 pm
 
Forum: Cell Biology
Topic: Inhibition of enzyme - will it result in upregulation?
Replies: 0
Views: 1882

The Fiber Disease

... strains of R. glutinis to eight antifungals and tested eight antiseptic agents on one strain of R. rubra. The tested strains were susceptible to ketoconazole, 5-fluorocytosine, amphotericin B, and nystatin, intermediate to econazole and resistant to fluconazole, itraconazole and miconazole. After ...

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by Nadas Moksha
Mon Nov 27, 2006 6:29 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479187

The Fiber Disease

... fragments (56, 100). Treatment of ocular pythiosis involves keratoplasty coupled with both topical (amphotericin B, natamycin, miconazole, and ketoconazole) and systemic (amphotericin B, ketoconazole, and itraconazole) antifungal agents (75). Despite these efforts, enucleation or evisceration ...

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by hartuk
Thu Nov 09, 2006 9:58 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479187

Why don't we have AIDS?

... success (47, 49). Surgical excision is recommended for small localized lesions. Amphotericin B and the azoles (itraconazole, fluconazole, and ketoconazole) appear to be the most effective medical treatment (11, 49, 67, 71, 93). Cure of olecranon bursitis generally requires bursectomy (47, ...

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by Sabrina
Fri Aug 25, 2006 8:26 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479187


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