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Kallmann syndrome

Kallmann syndrome

(Science: syndrome) congenital and familial disorder characterised by hypogonadotropic hypogonadism, eunuchoidal features, and anosmia or hyposmia. It is caused by a defect in the synthesis and/or release of lhrh (luteinizing hormone-releasing hormone; gonadorelin) from the hypothalamus as a result of faulty embryonic neuronal migration. The gene responsible for this is found in the region xp22.3 on the short arm of the x chromosome. There is a homolog on the y chromosome. The syndrome is more prevalent in males by a ratio of three to one.

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Androgen and oestrogen deficiency or inhibition

... oestrogens, or maybe even both, for instance in some diseases such as Kallmann's syndrome (although I am unsure both are totally lacking in this case), or caused by specific ...

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by Infotropism
Fri Aug 29, 2008 11:50 pm
Forum: Human Biology
Topic: Androgen and oestrogen deficiency or inhibition
Replies: 0
Views: 3396

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