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Jurkat cell

Definition

noun, plural: Jurkat cells

Any of the cells from an immortalized line of T lymphocytes (derived from the blood of a male patient with T-cell leukemia), primarily used in immunologic research.


Supplement

Jurkat (pronounced as yūr′kat) cells are used to study T lymphocyte behavior, cell signaling, and expression of chemokine receptors. The cells are also important in producing interleukin 2.


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Applicability of Jurkat cell line for cancer study

I want to do a comparative study between the CD4+ Jurkat T cell line and primary CD4+ T cells to study cancer. I cannot seem to find any papers using this in ...

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by songtree
Tue May 10, 2011 2:24 pm
 
Forum: Human Biology
Topic: Applicability of Jurkat cell line for cancer study
Replies: 0
Views: 889

Cluster of Differenciation(CD) replacement... Immunology

... are dozens of them. Or do you mean replacing the normal alpha/beta T cell receptor with the more rare gamma/delta chains? In mice you can produce ... studies you can genetically engineer immortalized T cells (such as Jurkat cells) by transferring the desired genes and then screening for gamma/delta ...

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by biohazard
Thu May 27, 2010 7:43 am
 
Forum: Molecular Biology
Topic: Cluster of Differenciation(CD) replacement... Immunology
Replies: 6
Views: 6317

Research assignment

... is as follow: i. Find 5 swedish and/or finnish biotech firms who uses cell biological assays in their research (this could be in cancer, stem cell ... FACS, annexin, GFP) iv. Identify what cells are being used (e. g. jurkat, hela cells) What approach should I have to this assignment.. I've ...

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by Lerhat
Sun May 03, 2009 6:50 pm
 
Forum: General Discussion
Topic: Research assignment
Replies: 0
Views: 1327


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