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Re: Any ideas for vaccine development or anti-viral drugs???

... sites for PMO based RNA-therapeutics followed by screening for effective viral gene target in mouse and guinea pig models utilizing adapted viral isolates. An evolution of chemical modifications were tested, beginning with simple Phosphorodiamidate Morpholino Oligomers (PMO) transitioning to cell ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 481

Campylobacter RFLP troubleshooting

I do not have any purpose of cloning.My aim is to type 300 Campylobacter strains molecularly and look for similarity between isolates; in short my aim is molcular typing. I am using RFLP just for that. Not for cloning or for something genetical method.

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by gislab03
Tue May 07, 2013 4:06 pm
Forum: Molecular Biology
Topic: Campylobacter RFLP troubleshooting
Replies: 4
Views: 2077

Re: Theories - Origin of Life

... an sound empirical observation. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC383146/ The low level of occurrence of tetracycline resistance among isolates from wild animals is presumably due to their low exposure to these antibiotics. Most of these isolates either had a high level of resistance ...

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by scottie
Fri Aug 17, 2012 3:46 pm
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 562
Views: 929259

Vaccine for HIV

... can evade the two major arms of the adaptive immune system; humoral (antibody-mediated) and cellular (mediated by T cells) immunity. Second, HIV isolates are themselves highly variable. HIV can be categorized into multiple clades and subtypes with a high degree of genetic divergence. Therefore, ...

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by suzidoc8
Mon Jul 23, 2012 2:47 pm
Forum: Microbiology
Topic: Vaccine for HIV
Replies: 1
Views: 7861

Hypothetical experiment

... on agar/same media for isolated colonies, etc. Prepare DNA for sequencing. Sequence whole genomes of samples from all 3 experiments. 6. Test all isolates for ability to utilize chemical introduced in c) by growing all isolates (from all experiments) in minimal media with this chemical as the ...

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by Cat
Tue Dec 06, 2011 8:54 pm
Forum: Evolution
Topic: Hypothetical experiment
Replies: 6
Views: 4611
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