Dictionary » I » Ion channel

Ion channel

Definition

noun, plural: ion channels

A single protein or protein complex that traverses the lipid bilayer of cell membrane and form a channel to facilitate the movement of ions through the membrane according to their electrochemical gradient


Supplement

Ion channels may be open or gated. The potassium leak channel is an example of open ion channel. Gated ion channels may be voltage-gated, ligand-gated, or mechanically-gated channels.

Ion channels are the common targets of pharmaceutical drugs, directly or indirectly, since they are capable of regulating the flow of ions to and from the cell. Many ions play in important physiological role in the normal metabolism of cells.

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Re: Depolarization = ion channel opening?

I think you are correct (or more precisely when the Na+ channels open since the K+ open later). There is a threshold voltage that switches the state of what I found to be a flip-flop. The circuit is also called a "monostable multivibrator".

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by GaryGaulin
Thu Jan 08, 2015 6:01 am
 
Forum: Cell Biology
Topic: Depolarization = ion channel opening?
Replies: 1
Views: 657

Depolarization = ion channel opening?

Hi huys, I have a problem with this statement: "Action potentials are formed when a stimulus causes the cell membrane to depolarize past the threshold of excitation, causing all sodium ion channels to open." Isn't the cell membrane depolarized ...

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by autumnsphere
Wed Oct 29, 2014 2:18 pm
 
Forum: Cell Biology
Topic: Depolarization = ion channel opening?
Replies: 1
Views: 657

[News] Frank Baker survives ''spontaneous combustion''

... he suddenly burst into flames, an experience he discusses for the first time on "The Unexplained Files," airing Oct. 2 on the Science Channel. "We were getting ready for fishing and sitting on the couch," Baker said on the episode. "Everything was great. [Friend] Pete ...

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by Coelacanth
Mon Feb 10, 2014 5:40 am
 
Forum: General Discussion
Topic: [News] Frank Baker survives ''spontaneous combustion''
Replies: 5
Views: 4213

Too many ions inside a neuron cell. What happens?

For example, there are diseases where the sodium channel cannot gauge voltage difference effectively, and so it remains open, rapidly building up a concentration of sodium ions in the cell, and this disorder often affects potassium channels, so there ...

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by Coelacanth
Tue Dec 03, 2013 1:34 am
 
Forum: General Discussion
Topic: Too many ions inside a neuron cell. What happens?
Replies: 1
Views: 2399

Cell Surafce Transmembrane Receptors

1.) What are the similarities between RTKs and Ion Channel Receptors? 2.) What are similarities between GPCRs and Ion Channel Receptors?

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by Sarahme33
Sat Nov 23, 2013 9:14 pm
 
Forum: Cell Biology
Topic: Cell Surafce Transmembrane Receptors
Replies: 0
Views: 1255
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