Dictionary » I » Ion channel

Ion channel


noun, plural: ion channels

A single protein or protein complex that traverses the lipid bilayer of cell membrane and form a channel to facilitate the movement of ions through the membrane according to their electrochemical gradient


Ion channels may be open or gated. The potassium leak channel is an example of open ion channel. Gated ion channels may be voltage-gated, ligand-gated, or mechanically-gated channels.

Ion channels are the common targets of pharmaceutical drugs, directly or indirectly, since they are capable of regulating the flow of ions to and from the cell. Many ions play in important physiological role in the normal metabolism of cells.

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Cell Surafce Transmembrane Receptors

1.) What are the similarities between RTKs and Ion Channel Receptors? 2.) What are similarities between GPCRs and Ion Channel Receptors?

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by Sarahme33
Sat Nov 23, 2013 9:14 pm
Forum: Cell Biology
Topic: Cell Surafce Transmembrane Receptors
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Views: 892

Re: SA node

... little piece of tissue located within the heart. Hence, the action of producing electrical impulses is equally as complex. I will try and ... ions (and to a lesser degree, Sodium) across the membrane through ion channels, which at different times open and close during the action potential. ...

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by jonjominns
Tue Sep 21, 2010 4:42 pm
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Topic: SA node
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Cell Membrane

... am practising for an exam and am not sure of the answers for these questions. A cell is placed into a solution that has the same osmolarity. However, ... of cells might be different (structurally) to each other? Is this about channel proteins and amount of lipid?

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by Nicolodn
Sat Sep 18, 2010 8:05 am
Forum: Cell Biology
Topic: Cell Membrane
Replies: 1
Views: 5530

Cystic fibrosis: amino acid deletion causes drastic results?

... just in case you didn't understand the part regarding why it stops functioning with a change in shape. chloride ion have a specific shape for it to pass through the channel should also have a specific shape. now for example made of 3 parts 1. you have ...

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by jwalin
Sat Jan 16, 2010 6:17 am
Forum: Molecular Biology
Topic: Cystic fibrosis: amino acid deletion causes drastic results?
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human physiology qu please help

... the first goes into the cleft binds to receptors on the second change ion receptor shape. a part also acts as Na + channel. Na+ flood in note this is a rough guideline. google synapsis. this mechanism has been ...

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by jwalin
Sat Dec 19, 2009 2:23 am
Forum: Physiology
Topic: human physiology qu please help
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