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Interleukin-3

Interleukin-3

(Science: cytokine) product of mitogen activated T-cells: colony-stimulating factor for bone marrow stem cells and mast cells.

a multilineage cell growth factor secreted by lymphocytes, epithelial cells, and astrocytes which stimulates clonal proliferation and differentiation of various types of blood and tissue cells. It is considered one of the haematopoietic colony-stimulating factors.

Synonym: multi-CSF

Acronym: IL-3


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Re: Cytokine - Receptor concepts

This is slightly out of my depth, but I can answer a few point that might help. There are usually more than one receptor for a type of interleukin on the cell surface, however some interleukins, when they are bound cause the cell to express more receptors of a particular type of interleukin, ...

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by Nataly56
Thu Jul 14, 2011 7:47 am
 
Forum: Cell Biology
Topic: Cytokine - Receptor concepts
Replies: 7
Views: 14501

Laboratory methods

... and Western blotting- not sure what they’re trying to extract and analyse here. Subcellular fractionation- Again, not too sure here. Effect of interleukin-6, IGF-I and BMSC on NVP-AEW541-induced growth inhibition- This is to see what effect these chemicals have on NVP-AEW541 In vitro kinase ...

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by lrob
Sun Mar 06, 2011 1:44 pm
 
Forum: Molecular Biology
Topic: Laboratory methods
Replies: 1
Views: 2208

Cytokine - Receptor concepts

... my questions. Here i am asking about the binding of the cytokines to their receptors on the cell surface. I've faced with texts like for example interleukin-12 binds to its receptor on T cells and initiates a change in the cell performance. I want to know that: Is there a unique IL-12 receptor ...

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by Saham
Fri May 21, 2010 5:22 pm
 
Forum: Cell Biology
Topic: Cytokine - Receptor concepts
Replies: 7
Views: 14501

Re: bifunctional proteins

Bifunctional proteins, obtainable by genetic manipulation, composed of an interleukin-2 and a granulocyte macrophage colony stimulating factor constituent have the biological activity of both components but are distinguished by increased stability. These proteins ...

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by ramseyedison
Wed Nov 04, 2009 6:19 am
 
Forum: Molecular Biology
Topic: bifunctional proteins
Replies: 4
Views: 4621

BLAST

Sometimes from the title like for X02532.1 it's "Human mRNA for interleukin 1 beta. Peripheral blood mononuclear cells", also, there is category SOURCE (in the sequence file, not at BLAST), but that is just the organism usually. So you will probably ...

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by JackBean
Mon Oct 12, 2009 4:44 am
 
Forum: Bioinformatics
Topic: BLAST
Replies: 9
Views: 22088
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