Dictionary » I » Interferons

Interferons

Interferon

(Science: cytokine) a family of glycoproteins derived from human cells which normally has a role in fighting viral infections by preventing virus multiplication in cells.

They are secreted by vertebrate cells in response to a wide variety of inducers and confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.

interferon-alpha is made by leucocytes and interferon-gamma by fibroblasts after viral infection. Interferon-alpha and -beta are also called type i interferons, interferon-gamma as type II interferons, more usually classed as cytokines.

Pharmacological action: antineoplastic agent, antiviral agents.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


In the chardakovs experiment...

... attacks only T-lymphocytes. But, we have our innate immunity left and our B-lymphocytes go unaffected by HIV. The Natural Killer Cells,macrophages,interferons,etc.... we still have many defences left. Why dont we find a way to stimulate them????????????

See entire post
by lisaa
Tue Dec 16, 2014 4:29 am
 
Forum: General Discussion
Topic: In the chardakovs experiment...
Replies: 4
Views: 6086

targeting the Aids virus

... attacks only T-lymphocytes. But, we have our innate immunity left and our B-lymphocytes go unaffected by HIV. The Natural Killer Cells,macrophages,interferons,etc.... we still have many defences left. Why dont we find a way to stimulate them????????????

See entire post
by Sumanth001
Fri Sep 27, 2013 12:31 pm
 
Forum: General Discussion
Topic: targeting the Aids virus
Replies: 3
Views: 3118

More general biology questions..

... there are "defective" and "non-defective" prions, and therefore mean that the above image is incorrect? 6. Wikipedia says that interferons are produced by lymphocytes, but my book seems to imply that they are produced by the (infected) cells themselves.Which is true? 7. With ...

See entire post
by freedompeace
Fri Apr 15, 2011 12:30 pm
 
Forum: Cell Biology
Topic: More general biology questions..
Replies: 1
Views: 6468

Re: Cytokine - Receptor concepts

... type of cells. Is important to know that Cytokines are proteins secreted by different types of cells like: (1) Lymphokines (2) Chemokines (3) Interferons (4) Colony- stimulating factors (5) Tumor necrosis factors Every cell acts in different ways on T cell. So different cytokines has different ...

See entire post
by marla
Tue Jun 01, 2010 9:08 pm
 
Forum: Cell Biology
Topic: Cytokine - Receptor concepts
Replies: 7
Views: 16935

Re: Allele symbols/acronyms?

... Kuhn, et. al. (1995) Science 269, 1427-1429. You put Cre recombinase under the control of a promoter (Mx1) which is sensitive to stimulation by interferons or polyinosinic-polycytidylic acid, a dsRNA sometimes abbreviated pIpC. That makes the recombinase inducible in whole animals. When induced, ...

See entire post
by blcr11
Wed Sep 10, 2008 4:20 pm
 
Forum: Genetics
Topic: Allele symbols/acronyms?
Replies: 7
Views: 10984
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 5,470 times. 
What links here | Related changes | Permanent link