Dictionary » I » Interferon-alpha



(Science: cytokine) One of the type i interferons produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded rna, or bacterial products.

It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral activity, causes activation of nk cells. It is used experimentally in the treatment of hairy-cell leukaemia.

a number of different subtypes exist that are elaborated by leukocytes in response to viral infection or stimulation with double-stranded RNA; IFN-alpha-2A and -2B are protein products made by recombinant dna techniques and are used as antineoplastic agents.

See: interferon-alpha 2a, interferon-alpha 2b

Synonym: leukocyte interferon.

Pharmacological action: antineoplastic agent, antiviral agent.

Please contribute to this project, if you have more information about this term feel free to edit this page

Results from our forum

Interferon production during viral infection

i want to asked that when virul infection takes place in cell , so how interferon are produced?

See entire post
Mon Sep 19, 2011 9:59 am
Forum: Microbiology
Topic: Interferon production during viral infection
Replies: 0
Views: 1043

The Best Biology Definitions

... very big lies Filter feeders ............... coffee drinkers Genital ............... kind and friendly Homeostasis ............... stays at home Interferon ............... to get in the way Melanin ............... referring to Mel and 'nem' Metacarpal ............... a big car pool Microbodies ...

See entire post
by aliengeek
Thu Jan 08, 2009 7:47 pm
Forum: General Discussion
Topic: The Best Biology Definitions
Replies: 3
Views: 5099

Prednisone stimulates Th1 but enhances th2 when discontinued

Prednisone blocks il-4 and il-10 thus increasing interferon gamma, an integral part of th1. But after it is discontinued, the il-4 and il-10 are worse than before the prednisone was started. Why is this?

See entire post
by hullcrush
Sun Nov 02, 2008 4:16 am
Forum: Human Biology
Topic: Prednisone stimulates Th1 but enhances th2 when discontinued
Replies: 1
Views: 2305

Re: What kills (and what saves) a corpus luteum?

... levels of PGF2 cut off the corpus luteum's blood supply, strangling it. In pregnant non-primates, it is known that the zygote produces interferon-gamma, which interferes with the PGF2 loop by blocking the genes which code for the receptors of estradiol and oxytocin; there is also suspected ...

See entire post
by jasonfahy
Mon May 05, 2008 4:58 pm
Forum: Human Biology
Topic: What kills (and what saves) a corpus luteum?
Replies: 3
Views: 12945

suggestions plz

... will end its replication proses right after its host is deead (because of lysis or protein machinery problem). Or in the second way, because of interferon, which is used to inhibit viral replication proceess....

See entire post
by victor
Fri Mar 02, 2007 12:56 pm
Forum: Microbiology
Topic: suggestions plz
Replies: 2
Views: 2047
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 1,027 times. 
What links here | Related changes | Permanent link