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Interferon-alpha

Interferon-alpha

(Science: cytokine) One of the type i interferons produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded rna, or bacterial products.

It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral activity, causes activation of nk cells. It is used experimentally in the treatment of hairy-cell leukaemia.

a number of different subtypes exist that are elaborated by leukocytes in response to viral infection or stimulation with double-stranded RNA; IFN-alpha-2A and -2B are protein products made by recombinant dna techniques and are used as antineoplastic agents.

See: interferon-alpha 2a, interferon-alpha 2b

Synonym: leukocyte interferon.

Pharmacological action: antineoplastic agent, antiviral agent.


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Interferon production during viral infection

i want to asked that when virul infection takes place in cell , so how interferon are produced?

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by WALDIA
Mon Sep 19, 2011 9:59 am
 
Forum: Microbiology
Topic: Interferon production during viral infection
Replies: 0
Views: 911

The Best Biology Definitions

... very big lies Filter feeders ............... coffee drinkers Genital ............... kind and friendly Homeostasis ............... stays at home Interferon ............... to get in the way Melanin ............... referring to Mel and 'nem' Metacarpal ............... a big car pool Microbodies ...

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by aliengeek
Thu Jan 08, 2009 7:47 pm
 
Forum: General Discussion
Topic: The Best Biology Definitions
Replies: 3
Views: 4645

Prednisone stimulates Th1 but enhances th2 when discontinued

Prednisone blocks il-4 and il-10 thus increasing interferon gamma, an integral part of th1. But after it is discontinued, the il-4 and il-10 are worse than before the prednisone was started. Why is this?

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by hullcrush
Sun Nov 02, 2008 4:16 am
 
Forum: Human Biology
Topic: Prednisone stimulates Th1 but enhances th2 when discontinued
Replies: 1
Views: 2051

Re: What kills (and what saves) a corpus luteum?

... levels of PGF2 cut off the corpus luteum's blood supply, strangling it. In pregnant non-primates, it is known that the zygote produces interferon-gamma, which interferes with the PGF2 loop by blocking the genes which code for the receptors of estradiol and oxytocin; there is also suspected ...

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by jasonfahy
Mon May 05, 2008 4:58 pm
 
Forum: Human Biology
Topic: What kills (and what saves) a corpus luteum?
Replies: 3
Views: 11109

suggestions plz

... will end its replication proses right after its host is deead (because of lysis or protein machinery problem). Or in the second way, because of interferon, which is used to inhibit viral replication proceess....

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by victor
Fri Mar 02, 2007 12:56 pm
 
Forum: Microbiology
Topic: suggestions plz
Replies: 2
Views: 1806
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