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Interferon

Interferon

(Science: cytokine) a family of glycoproteins derived from human cells which normally has a role in fighting viral infections by preventing virus multiplication in cells.

They are secreted by vertebrate cells in response to a wide variety of inducers and confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.

interferon-alpha is made by leucocytes and interferon-gamma by fibroblasts after viral infection. Interferon-alpha and -beta are also called type i interferons, interferon-gamma as type II interferons, more usually classed as cytokines.

Pharmacological action: antineoplastic agent, antiviral agents. An antiviral protein produced by cells that have been invaded by a virus; inhibits replication of the virus.A type of glycoprotein that is produced as a defense mechanism against [[pathogens.


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... very big lies Filter feeders ............... coffee drinkers Genital ............... kind and friendly Homeostasis ............... stays at home Interferon ............... to get in the way Melanin ............... referring to Mel and 'nem' Metacarpal ............... a big car pool Microbodies ...

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by aliengeek
Thu Jan 08, 2009 7:47 pm
 
Forum: General Discussion
Topic: The Best Biology Definitions
Replies: 3
Views: 599

Prednisone stimulates Th1 but enhances th2 when discontinued

Prednisone blocks il-4 and il-10 thus increasing interferon gamma, an integral part of th1. But after it is discontinued, the il-4 and il-10 are worse than before the prednisone was started. Why is this?

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by hullcrush
Sun Nov 02, 2008 4:16 am
 
Forum: Human Biology
Topic: Prednisone stimulates Th1 but enhances th2 when discontinued
Replies: 1
Views: 619

Re: What kills (and what saves) a corpus luteum?

... levels of PGF2 cut off the corpus luteum's blood supply, strangling it. In pregnant non-primates, it is known that the zygote produces interferon-gamma, which interferes with the PGF2 loop by blocking the genes which code for the receptors of estradiol and oxytocin; there is also suspected ...

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by jasonfahy
Mon May 05, 2008 4:58 pm
 
Forum: Human Biology
Topic: What kills (and what saves) a corpus luteum?
Replies: 3
Views: 1667

suggestions plz

... will end its replication proses right after its host is deead (because of lysis or protein machinery problem). Or in the second way, because of interferon, which is used to inhibit viral replication proceess....

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by victor
Fri Mar 02, 2007 12:56 pm
 
Forum: Microbiology
Topic: suggestions plz
Replies: 2
Views: 932

how to detect dsRNA ?

... "small activating RNA (saRNA)". Double-stranded (ds) RNA, a common component of virus-infected cells, is a potent inducer of the type I interferon and other cellular genes. For identifying the full repertoire of human dsRNA-regulated genes, a cDNA microarray hybridization screening was ...

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by dipjyoti
Sun Feb 18, 2007 10:47 am
 
Forum: Molecular Biology
Topic: how to detect dsRNA ?
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Views: 955
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