Dictionary » I » Initiation codon

Initiation codon

Initiation codon

The codon 5' AUG in mrna, at which polypeptide synthesis is started. It is recognised by formylmethionyl trna in bacteria and by methionyl trna in eukaryotes. A codon that is responsible for activating the translation of dna to mrna, usually with the sequence of AUG or GUG.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Re: How to knock down a gene?

... processes; a typical application is to bind in the 5'-UTR and halt the initiation complex as it travels from the 5'-cap to the start codon, preventing ribosome assembly. A single strand of RNAi oligos is loaded into the RISC ...

See entire post
by jonmoulton
Fri Oct 31, 2008 6:46 pm
 
Forum: Genetics
Topic: How to knock down a gene?
Replies: 1
Views: 811

Re: Morpholino review: how to knockdown

... a Morpholino can target anywhere between the 5' cap and the start codon and can extend downstream into the coding sequence as long as the start ... and the small ribosomal subunit bind at the 5' cap and then other initiation factors bind, forming the initiation complex. The initiation complex ...

See entire post
by jonmoulton
Mon Aug 04, 2008 5:30 pm
 
Forum: Molecular Biology
Topic: Morpholino review: how to knockdown
Replies: 7
Views: 1748

Re: computational gene prediction

... Uberbacher and Mural (1991); Uberbacher et al. (1996) Initiation codon analysis http://www.ncbi.nlm.nih.gov/htbin-post/Taxonomy/wprintgc?mode=c Microbial genome ...

See entire post
by ani1977
Wed Apr 11, 2007 10:59 am
 
Forum: Bioinformatics
Topic: computational gene prediction
Replies: 4
Views: 2612

The Fiber Disease

... so you may want to look further on your own. It has to do with the codon triplets, mainly the "stop codons" in particular. Here is ... before the organism is viable. Translation starts with a chain initiation codon (start codon). Unlike stop codons, the codon alone is not ...

See entire post
by codon blue
Mon Dec 11, 2006 12:46 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 749501

The Fiber Disease

... and a model in which DsrA interacts with the hns mRNA start and stop codon regions to form a coaxial stack. Analogous bipartite interactions exist ... prokaryotic viruses and chloroplast proteins. As in the standard code, initiation is most efficient at AUG. In addition, GUG and UUG starts are ...

See entire post
by Skytroll
Wed Sep 06, 2006 4:29 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 749501
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 518 times. 
What links here | Related changes | Permanent link