Inhibition factor

Inhibition factor --> migration-inhibitory factor

(Science: growth factor) a soluble, nondialysable factor that is produced by sensitised lymphocytes following exposure to a specific antigen. It inhibits macrophage migration and causes adherence.

It was originally defined on the basis of inhibition of emigration of mononuclear cells from capillary (haematocrit) tubes, more recently a 13 kd protein with migration inhibitory activity has been isolated.

Acronym: mif

Synonym: inhibition factor.

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