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Inhibin

(Science: hormone) polypeptide hormone secreted by the hypophysis, that selectively suppresses the secretion of pituitary follicle-stimulating hormone. The molecule has two subunits (14 & 18 kD) and is a product of the gene family that includes tgf _. There are two forms, __A and __B, the _ subunit being shared with activin.

inhibin is now, on the basis of gene knockout experiments, considered to be a tumour suppressor, the key gene being that for inhibin _.