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Incomplete penetrance



A form of penetrance in which not all individuals carrying a deleterious gene express the associated trait or condition.


A disease is said to show incomplete penetrance when some individuals express the associated trait while others do not even though they carry the disease-causing gene. For instance, some people with a mutation in the BRCA1 or BRCA2 gene will develop cancer during their lifetime, other people will not.

‘’Synonym:’’ reduced penetrance

Compare: complete penetrance

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Dominance but not majority? Why?!

... polydactyly is controlled by a dominant allele it is accompanied by incomplete penetrance hence not observed in majority of the population. The gene doesnot penetrate or ...

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by M.Shanti Priya
Thu Feb 02, 2006 9:52 am
Forum: Genetics
Topic: Dominance but not majority? Why?!
Replies: 5
Views: 2371

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