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Immunological synapse



A form of synapse between a lymphocyte and an antigen-presenting cell.


It was first discovered by Abraham Kupfer at the National Jewish Center in Denver. It has been named as such since it resembles the synapses of the nervous system. An example of such synapse is a T lymphocyte in synapse with a major histocompatibility complex molecule on the antigen-presenting cell.

See also: synapse.

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Lipid Trafficking

... cells do not get activated unnecessarily. This phenomenon is called an immunological synapse. Somewhat similar synapse is also formed by cytotoxic (CD8) lymphocytes and MHC I-expressing ...

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by biohazard
Tue Dec 09, 2008 8:01 am
Forum: Cell Biology
Topic: Lipid Trafficking
Replies: 6
Views: 5198

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