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Immune tolerance



The lack of, or low level, response of the immune system towards an antigen, especially a tolerogen.


Immune tolerance that occurs under normal conditions is during pregnancy when the fetus and the placenta must be tolerated by the maternal immune system.

Immune tolerance may also be induced, for example during organ transplantation when the immune system must be forced to become unresponsive in order to accept an organ from another individual.

Word origin: immune + tolerance.

Variant: immunological tolerance

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Sperm Immunity of Womens

Sperm are immunogenic - that is they will cause an autoimmune reaction if transplanted from the testis into a different part of the ... likely reason for this is that sperm first mature at puberty, after immune tolerance is established, therefore the body recognizes them as foreign and mounts ...

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by ankitaalive
Wed Nov 28, 2012 6:28 am
Forum: Cell Biology
Topic: Sperm Immunity of Womens
Replies: 1
Views: 2796

Re: Theories - Origin of Life

... of? Again lets not speculate Here is some interesting information of immune system response to gene alterations from the Stanford School of Medicine. ... design principles of cellular control [e.g., robustness (5, 6), noise tolerance (7), programmed temporal order (8, 11), sign-sensitive dynamics ...

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by scottie
Tue Jan 17, 2012 11:04 pm
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 563
Views: 1127899

Re: Blood type changing spontaneously with a transplant?

... reply, but some people (myself included) thought about how the new immune system would recognize the original host tissue as own, and not launch ... probably work for foreign T-cells as well, hence the the new system's tolerance to the original tissue types: only T-cells that recognize the original ...

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by biohazard
Tue Mar 04, 2008 9:46 am
Forum: Human Biology
Topic: Blood type changing spontaneously with a transplant?
Replies: 18
Views: 32443

Re: Blood type changing spontaneously with a transplant?

... see how this 'switch of blood type' could take place. The cells of the immune system are still in the person's body, and if this person's blood ... own tissues, which would probably cause problems with lymphocytes' self-tolerance (i.e. their ability to recognize host tissues as non-immunogenic). ...

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by biohazard
Mon Mar 03, 2008 1:52 pm
Forum: Human Biology
Topic: Blood type changing spontaneously with a transplant?
Replies: 18
Views: 32443

Sugar Allergy

... products, gluten containing foods and how to recognize a fructose intolerance. Then there's Celiac Disease and the inflammatory cascade caused ... 38. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev. 1999;4(2):96-103. 39. Hagmar ...

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by DrDahlman
Sat Jan 12, 2008 4:20 pm
Forum: Human Biology
Topic: Sugar Allergy
Replies: 76
Views: 287689
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